SCN1A antibody (AA 992-1099)

Catalog No. ABIN7169916

Product Details anti-SCN1A Antibody

Target: SCN1A (Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A))

Binding Specificity: AA 992-1099

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCN1A antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Sodium channel protein type 10 subunit alpha protein (992-1099AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SCN1A

Target: SCN1A (Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A))

Alternative Name: SCN1A (SCN1A Products)

Background:

Background: Tetrodotoxin-resistant channel that mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. Plays a role in neuropathic pain mechanisms.

Aliases: hPN3 antibody, mPN3 antibody, Peripheral nerve sodium channel 3 antibody, Pn3 (gene name) antibody, PN3 antibody, SCN10A antibody, SCNAA_HUMAN antibody, Sensory neuron sodium channel antibody, Sns (gene name) antibody, SNS antibody, Sodium channel protein type 10 subunit alpha antibody, Sodium channel protein type X alpha subunit antibody, Sodium channel protein type X subunit alpha antibody, Voltage-gated sodium channel alpha subunit Nav1.8 antibody, Voltage-gated sodium channel subunit alpha Nav1.8 antibody

UniProt: Q9Y5Y9