SCN1A antibody (AA 1901-2009)
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- Target See all SCN1A Antibodies
- SCN1A (Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A))
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Binding Specificity
- AA 1901-2009
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SCN1A antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human SCN1A
- Isotype
- IgG
- Top Product
- Discover our top product SCN1A Primary Antibody
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- Application Notes
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- SCN1A (Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A))
- Alternative Name
- SCN1A (SCN1A Products)
- Synonyms
- SCN9A antibody, SCN1A antibody, B230332M13 antibody, Nav1.1 antibody, EIEE6 antibody, FEB3 antibody, FEB3A antibody, FHM3 antibody, GEFSP2 antibody, HBSCI antibody, NAC1 antibody, SCN1 antibody, SMEI antibody, sodium voltage-gated channel alpha subunit 1 antibody, sodium voltage-gated channel alpha subunit 9 antibody, sodium channel, voltage-gated, type I, alpha antibody, SCN1A antibody, SCN9A antibody, Scn1a antibody
- Background
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Synonyms: alpha, brain sodium channel type I, EIEE6, FEB3, FEB3A, FHM3, GEFS+2, GEFSP2, HBSC I, HBSCI, MIM 182390, NAC1, Nav 1.1, RBI, SCN1, Scn1a, SCN1A_HUMAN, SCN2A1, SMEI, sodium channel, Sodium channel protein brain I alpha subunit, Sodium channel protein brain I subunit alpha, Sodium channel protein type 1 subunit alpha, Sodium channel protein type I subunit alpha, Sodium channel voltage gated type 1 alpha subunit, Sodium channel voltage gated type I alpha polypeptide, type I, voltage gated, Voltage-gated sodium channel subunit alpha Nav1.1.
Background: SCN1A is a voltage-gated ion channel essential for the generation and propagation of action potentials, mainly in nerve and muscle. Voltage-sensitive sodium channels are heteromeric complexes consisting of a large central pore-forming glycosylated alpha subunit, and two smaller auxiliary beta subunits. This gene encodes the large alpha subunit, and mutations in this gene have been associated with several epilepsy, convulsion and migraine disorders. Alternative splicing results in multiple transcript variants. The RefSeq Project has decided to create four representative RefSeq records. Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons, the exact combination of which have not been experimentally confirmed for the full-length transcript
- Gene ID
- 6323
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