DPF1 antibody (AA 261-380)

Catalog No. ABIN7176590

Product Details anti-DPF1 Antibody

Target: DPF1 (D4, Zinc and Double PHD Fingers Family 1 (DPF1))

Binding Specificity: AA 261-380

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPF1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Zinc finger protein neuro-d4 protein (261-380AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DPF1

Target: DPF1 (D4, Zinc and Double PHD Fingers Family 1 (DPF1))

Alternative Name: DPF1 (DPF1 Products)

Background:

Background: May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).

Aliases: BAF45B antibody, BRG1-associated factor 45B antibody, D4 antibody, D4 zinc and double PHD fingers family 1 antibody, DPF1 antibody, DPF1_HUMAN antibody, NEUD4 antibody, Neuro d4 homolog antibody, Zinc and double PHD fingers family 1 antibody, Zinc finger protein neuro-d4 antibody

UniProt: Q92782