Iba1 antibody (AA 2-147) (Biotin)

Catalog No. ABIN7176925

Product Details anti-Iba1 Antibody (Biotin)

Target: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Binding Specificity: AA 2-147

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Iba1 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Mouse Allograft inflammatory factor 1 protein (2-147AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Iba1

Target: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Alternative Name: Aif1 (IBA1 Products)

Background:

Background: Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

Aliases: Aif1 antibody, Iba1Allograft inflammatory factor 1 antibody, AIF-1 antibody, Ionized calcium-binding adapter molecule 1 antibody

UniProt: O70200

Pathways: Smooth Muscle Cell Migration