GTF2H2 antibody (N-Term)

Catalog No. ABIN7184511

Product Details anti-GTF2H2 Antibody

Target: GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTF2H2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human, Mouse, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from N-terminal of Human TF2H2.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GTF2H2

Target: GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))

Alternative Name: GTF2H2 (GTF2H2 Products)

Background:

Background: Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. The N-terminus interacts with and regulates XPD whereas an intact C-terminus is required for a successful escape of RNAP II form the promoter.

Humbert S., EMBO J. 13:2393-2398(1994).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
van der Steege G., Eur. J. Hum. Genet. 3:87-95(1995).

Aliases: Basic transcription factor 2 44 kDa subunit antibody, BTF2 antibody, BTF2 p44 antibody, BTF2-p44 antibody, BTF2P44 antibody, General transcription factor IIH antibody, General transcription factor IIH polypeptide 2 antibody, General transcription factor IIH subunit 2 antibody, General transcription factor IIH, polypeptide 2, 44 kDa antibody, Gtf2h2 antibody, MGC102806 antibody, p44 antibody, T BTF2P44 antibody, T-BTF2P44 antibody, TF2H2_HUMAN antibody, TFIIH antibody, TFIIH basal transcription factor complex p44 subunit antibody

UniProt: Q13888

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling