COL1A1 antibody (AA 1219-1464)
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- Target See all COL1A1 Antibodies
- COL1A1 (Collagen, Type I, alpha 1 (COL1A1))
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Binding Specificity
- AA 1219-1464
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This COL1A1 antibody is un-conjugated
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Application
- ELISA, Flow Cytometry (FACS)
- Purpose
- COL1A1 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human COL1A1 (AA: 1219-1464) expressed in E. Coli.
- Clone
- 7B1G12
- Isotype
- IgG1
- Top Product
- Discover our top product COL1A1 Primary Antibody
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- COL1A1 (Collagen, Type I, alpha 1 (COL1A1))
- Alternative Name
- COL1A1 (COL1A1 Products)
- Background
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Description:
This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
Aliases: OI1, OI2, OI3, OI4, EDSC, EDSARTH1
- Molecular Weight
- 139kDa
- Gene ID
- 1277
- UniProt
- P02452
- Pathways
- Sensory Perception of Sound, Autophagy, Growth Factor Binding
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