ABCC3 antibody (AA 849-963)

Catalog No. ABIN7193703

Product Details anti-ABCC3 Antibody

Target: ABCC3 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3))

Binding Specificity: AA 849-963

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ABCC3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: MRP3 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human MRP3 (AA: 849-963) expressed in E. Coli.

Clone: 1A2F6

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for ABCC3

Target: ABCC3 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3))

Alternative Name: MRP3 (ABCC3 Products)

Background:

Description:

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined, however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.

Aliases: ABCC3, MLP2, ABC31, MOAT-D, cMOAT2, EST90757

Molecular Weight: 169.3kDa

Gene ID: 8714

UniProt: O15438