ABCC3 antibody

Catalog No. ABIN7073148

The Rabbit Polyclonal anti-ABCC3 antibody is suitable to detect ABCC3 in samples from Human, Rat and Mouse. It has been validated for WB.

Quick Overview for ABCC3 antibody (ABIN7073148)

Target: ABCC3 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCC3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ABCC3 Antibody

Cross-Reactivity: Mouse, Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Human MRP3

Application Details

Application Notes: WB (H,M,R) 1: 500-1: 1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for ABCC3

Target: ABCC3 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3))

Alternative Name: MRP3

Background: The protein encoded by this gene is a member of the super family of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes.

Molecular Weight: 170 kDa

Gene ID: 76408

NCBI Accession: NP_001137542

UniProt: O15438