HDAC8 antibody
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- Target See all HDAC8 Antibodies
- HDAC8 (Histone Deacetylase 8 (HDAC8))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This HDAC8 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- Purpose
- [KO Validated] HDAC8 Rabbit mAb
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Monoclonal Antibodies
- Purification
- Affinity purification
- Grade
- KO Validated
- Immunogen
- A synthesized peptide derived from human HDAC8
- Isotype
- IgG
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- HDAC8 (Histone Deacetylase 8 (HDAC8))
- Alternative Name
- HDAC8 (HDAC8 Products)
- Background
- Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009],CDA07, CDLS5, HD8, HDACL1, MRXS6, RPD3, WTS,Cardiovascular,Epigenetics & Nuclear Signaling,Heart,Heart_Hypertrophy,Immunology & Inflammation,NF-kB Signaling Pathway,Nuclear Receptor Signaling,Stem Cells,HDAC8
- Molecular Weight
- 42kDa
- Gene ID
- 55869
- UniProt
- Q9BY41
- Pathways
- Cellular Glucan Metabolic Process
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