Adenylosuccinate Lyase antibody (AA 200-250)

Catalog No. ABIN7449945

Product Details anti-Adenylosuccinate Lyase Antibody

Target: Adenylosuccinate Lyase (ADSL)

Binding Specificity: AA 200-250

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adenylosuccinate Lyase antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-Adenylosuccinate Lyase/ADSL Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 200 and 250

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Adenylosuccinate Lyase

Target: Adenylosuccinate Lyase (ADSL)

Alternative Name: Adenylosuccinate Lyase/ADSL (ADSL Products)

Background: Background: Adenylosuccinate Lyase / ADSL is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and, in some cases, growth retardation associated with muscle wasting and epilepsy [taken from NCBI Entrez Gene (Gene ID: 158)].

Gene ID: 158

UniProt: P30566

Pathways: Ribonucleoside Biosynthetic Process