KLRF1 antibody (Extracellular Domain) (PE)

Catalog No. ABIN7540463

Product Details anti-KLRF1 Antibody (PE)

Target: KLRF1 (Killer Cell Lectin-Like Receptor Subfamily F, Member 1 (KLRF1))

Binding Specificity: Extracellular Domain

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KLRF1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Purpose: Anti-Hu NKp80 PE

Specificity: The mouse monoclonal antibody 5D12 recognizes an extracellular epitope of human NKp80 (CLEC5C), a C-type lectin family member, expressed on NK cells and subsets of T cells.

No Cross-Reactivity: Mouse, Rat

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: recombinant human NKp80 extracellular domain

Clone: 5D12

Isotype: IgG1 kappa

Application Details

Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details for KLRF1

Target: KLRF1 (Killer Cell Lectin-Like Receptor Subfamily F, Member 1 (KLRF1))

Alternative Name: NKp80 (KLRF1 Products)

Background:

NCBI Full Gene Name: killer cell lectin like receptor F1

Description: NKp80, also known as CLEC5C or KLRF1, is a type II transmembrane glycoprotein of the C lectin family, which is expressed in 80 kDa homodimers on NK cells, and subsets of CD8+ alpha/beta T cells, and gamma/delta T cells. It belongs to the activating coreceptors, which induce cytotoxicity, and production of pro-inflammatory cytokines. Its ligand AICL is expressed on myeloid cells.

Other names: KLRF1, CLEC5C

Gene name: KLRF1

Gene ID: 51348

UniProt: Q9NZS2