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BCR antibody (AA 1201-1271) (Biotin)

BCR Reactivity: Human, Mouse, Rat ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal Biotin

Catalog No. ABIN750025

Datasheet as PDF

Target See all BCR Antibodies

BCR (Breakpoint Cluster Region (BCR))
Binding Specificity
30

15

8

4

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1201-1271
Reactivity
95

52

24

4

2

2

1

1

1

1
Human, Mouse, Rat
Host
88

4

4
Rabbit
Compatible Secondaries
Clonality
91

5
Polyclonal
Conjugate
57

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1
This BCR antibody is conjugated to Biotin
Application
68

36

32

26

26

23

18

14

9

5

5

4

3

2

1

1
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity

Human, Mouse, Rat

Predicted Reactivity

Dog,Cow,Horse,Chicken,Rabbit

Purification

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human Bcr

Isotype

IgG

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BCR Reactivity: Human, Mouse WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

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BCR Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated

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BCR Reactivity: Human, Mouse WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

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BCR Reactivity: Human WB, PLA Host: Rabbit Polyclonal unconjugated

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BCR Reactivity: Human, Mouse WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (pTyr177) antibody
BCR Reactivity: Human WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (pTyr360) antibody
BCR Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated

Application Notes

IHC-P 1:200-400
IHC-F 1:100-500

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

Store at -20°C for 12 months.

Expiry Date

12 months
Target

BCR (Breakpoint Cluster Region (BCR))

Alternative Name

Bcr (BCR Products)

Background

Synonyms: ALL, BCR 1, BCR/ABL FUSION GENE INCLUDED, BCR/FGFR1 FUSION GENE INCLUDED, BCR/PDGFRA FUSION GENE INCLUDED, BCR1, breakpoint cluster region, CML, PHL, BCR_HUMAN.
Background: The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.

Gene ID

613

Pathways

Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling