Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A) (AA 310-360) antibody Primary Antibody

IDH3A Reactivity: Human, Mouse, Rat IF (p), IHC (p), WB Host: Rabbit Polyclonal unconjugated
Pubmed (1)
Catalog No. ABIN751543
$339.90
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 4 to 6 Business Days
  • Target
    Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A)
    Binding Specificity
    • 14
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 310-360
    Reactivity
    • 35
    • 27
    • 26
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 30
    • 4
    • 1
    Rabbit
    Clonality
    • 32
    • 3
    Polyclonal
    Conjugate
    • 16
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Un-conjugated
    Application
    • 19
    • 12
    • 9
    • 8
    • 5
    • 5
    • 3
    • 1
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human IDH3A
    Isotype
    IgG
  • Application Notes
    WB 1:100-1000
    IHC-P 1:100-500
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C
    Expiry Date
    12 months
  • Xing, Yuan, Xu, Gu, Liang, Lu: "Proteomic identification of mitochondrial targets involved in andrographolide sodium bisulfite-induced nephrotoxicity in a rat model." in: Environmental toxicology and pharmacology, Vol. 40, Issue 2, pp. 592-9, 2015 (PubMed). Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)). Further details: Sample: Kidney

  • Target
    Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A)
    Alternative Name
    Idh3a (IDH3A Antibody Abstract)
    Synonyms
    idh3a, MGC76128, IDH3A, zgc:56380, zgc:85631, BG1, 1110003P10Rik, 1500012E04Rik, AA407078, AI316514, isocitrate dehydrogenase 3 (NAD+) alpha, isocitrate dehydrogenase 3 (NAD(+)) alpha, isocitrate dehydrogenase 3 (NAD+) alpha S homeolog, idh3a, IDH3A, idh3a.S, Idh3a
    Background

    Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. IDH3A is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.

    Subcellular location: Mitochondrion

    Synonyms: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitric dehydrogenase subunit alpha, NAD(+)-specific ICDH subunit alpha, IDH3A

    Gene ID
    3419
    UniProt
    P50213
You are here:
help Support