NLRX1 antibody (N-Term)

Catalog No. ABIN783701

The Rabbit Polyclonal anti-NLRX1 antibody has been validated for WB and EIA. It is suitable to detect NLRX1 in samples from Human, Rat and Mouse.

Quick Overview for NLRX1 antibody (N-Term) (ABIN783701)

Target: NLRX1 (NLR Family Member X1 (NLRX1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRX1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-NLRX1 Antibody

Binding Specificity: N-Term

Specificity: This antibody detects NLRX1 / NOD9 at N-term.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 14 amino acid peptide near the amino terminus of human NOD5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for NLRX1

Target: NLRX1 (NLR Family Member X1 (NLRX1))

Alternative Name: NLRX1 / NOD9

Background: NOD5, also known as NLRX1, is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD5 localizes to the mitochondrial outer membrane and interacts with the virus-induced signaling adapter protein VISA. Unlike a subset of NOD-like receptors (NLRs) such as NOD1 and NOD2 which trigger pro-inflammatory cascades, and other NLRs that induce the caspase 1 inflammasome in response to immune challenges, NOD5 amplifies NF-kB and JNK pathways by inducing reactive oxygen species production.Synonyms: Caterpiller 11.3, NLR family member X1, NOD26, NOD5, Nucleotide-binding oligomerization domain protein 26, Nucleotide-binding oligomerization domain protein 5, Nucleotide-binding oligomerization domain protein 9

Gene ID: 79671

NCBI Accession: NP_078894

UniProt: Q86UT6

Pathways: SARS-CoV-2 Protein Interactome