SLC39A14 antibody (Center)

Catalog No. ABIN783817

Product Details anti-SLC39A14 Antibody

Target: SLC39A14 (Solute Carrier Family 39 (Zinc Transporter), Member 14 (SLC39A14))

Binding Specificity: Center

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC39A14 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificity: This antibody detects Zinc transporter ZIP14 / SLC39A14 at Center.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the center of human ZIP14

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for SLC39A14

Target: SLC39A14 (Solute Carrier Family 39 (Zinc Transporter), Member 14 (SLC39A14))

Alternative Name: Zinc Transporter ZIP14 / SLC39A14 (SLC39A14 Products)

Synonyms: LZT-Hs4 antibody, NET34 antibody, ZIP14 antibody, cig19 antibody, BC021530 antibody, G630015O18Rik antibody, Zip14 antibody, fad123 antibody, solute carrier family 39 member 14 antibody, solute carrier family 39 (zinc transporter), member 14 antibody, SLC39A14 antibody, Slc39a14 antibody

Background: The zinc transporter ZIP14, also known as SLC39A14, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP14 is a glycosylated multipass plasma membrane protein that belongs to the ZIP transporter subfamily LIV-1. ZIP14 has been shown to contribute to the hypozincemia of inflammation and infection and is regulated in the liver by IL-6. In addition to zinc, ZIP14 is also involved in the cellular uptake of non-transferrin-bound iron as well as iron bound to transferrin (6).Synonyms: KIAA0062, LIV-1 subfamily of ZIP zinc transporter 4, LZT-Hs4, Solute carrier family 39 member 14, ZIP-14, ZIP14, Zrt- and Irt-like protein 14

Gene ID: 23516

NCBI Accession: NP_001121903

UniProt: Q15043

Pathways: Transition Metal Ion Homeostasis