Nerve Growth Factor Receptor (TNFRSF16) Associated Protein 1 (NGFRAP1) (AA 34-111) antibody (AbBy Fluor® 350)

Catalog No. ABIN907578

Product Details

Target: Nerve Growth Factor Receptor (TNFRSF16) Associated Protein 1 (NGFRAP1)

Binding Specificity: AA 34-111

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: AbBy Fluor® 350

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NADE/NGFRAP1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Nerve Growth Factor Receptor (TNFRSF16) Associated Protein 1 (NGFRAP1)

Alternative Name: NGFRAP1 (NGFRAP1 Products)

Background:

Synonyms: BEX3, BEX3_HUMAN, Brain expressed X linked 3 mouse homolog, Brain-expressed X-linked protein 3, Nerve growth factor receptor TNFRSF16 associated protein 1, Nerve growth factor receptor associated protein 1, Nerve growth factor receptor-associated protein 1, NGFRAP1, Ovarian granulosa cell 13.0 kDa protein HGR74, Ovarian granulosa cell protein, p75NTR associated cell death executor, p75NTR-associated cell death executor, Protein BEX3.

Background: May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.Tissue specificity: Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.

Gene ID: 27018

Pathways: Neurotrophin Signaling Pathway, Positive Regulation of Endopeptidase Activity