NFKBIZ antibody (C-Term)

Catalog No. ABIN928976

Product Details anti-NFKBIZ Antibody

Target: NFKBIZ (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, zeta (NFKBIZ))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFKBIZ antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine)

Purification: Purified

Immunogen: Nfkbiz antibody was raised in rabbit using the C terminal of Nfkbiz as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

Nfkbiz Blocking Peptide, catalog no. 33R-9778, is also available for use as a blocking control in assays to test for specificity of this Nfkbiz antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for NFKBIZ

Target: NFKBIZ (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, zeta (NFKBIZ))

Alternative Name: Nfkbiz (NFKBIZ Products)

Background: Nfkbiz is involved in regulation of NF-kappa-B transcription factor complexes. It inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation. It inhibits DNA-binding of RELA and NFKB1/p50, and of the NF-kappa-B p65-p50 heterodimer and the NF-kappa-B p50-p50 homodimer. It seems also to activate NF-kappa-B-mediated transcription. In vitro, upon association with NFKB1/p50, Nfkbiz has transcriptional activation activity and, together with NFKB1/p50 and RELA, Nfkbiz is recruited to LCN2 promoters. Synonyms: Polyclonal Nfkbiz antibody, Anti-Nfkbiz antibody, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta antibody, AA408868 antibody, INAP antibody, Mail antibody.

Pathways: NF-kappaB Signaling