CD58 antibody (CD58 Molecule) (Biotin)

Details for Product anti-CD58 Antibody No. ABIN94196
Antigen
Reactivity
Human, Pig (Porcine)
206
16
10
6
4
Host
Mouse
126
84
Clonality (Clone)
Monoclonal ()
Conjugate
This CD58 antibody is conjugated to Biotin
31
23
16
15
4
4
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
119
69
34
14
13
13
12
10
6
5
3
2
2
Options
Immunogen NALM-6 human pre-B cell line
Clone MEM-63
Isotype IgG1
Specificity The antibody MEM-63 reacts with CD58 (LFA-3), a 40-70 kDa glycoprotein distributed over many tissues, leukocytes, erythrocytes, endothelial cells, epithelial cells and fibroblasts.
HLDA VI, WS Code AS A047
Cross-Reactivity (Details) Porcine, Human
Antigen
Alternative Name CD58 (CD58 Antibody Abstract)
Background CD58 (LFA-3) is an immunoglobulin family adhession molecule expressed by both hematopoietic and non-hematopoietic cells (often on antigen presenting cells) and serving as ligand of CD2. This interaction is important for T cell-mediated immunity. CD58 is expressed in transmembrane form and in GPI-anchored form, the later is constitutively associated with protein kinases whereas the transmembrane form activates kinase activity upon triggering. CD58 is a powerful tool for detection of minimal residual disease in acute lymphocytic leukemia, and for evaluation of liver damage related with hepatitis B.
Application Notes Biotinylated antibody is designed for indirect immunofluorescence analysis by Flow Cytometry.Suggested working dilution is 1:200. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.
Comment

The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.

Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Tris buffered saline (TBS) with 15 mM sodium azide, approx. pH 8.0
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Avoid prolonged exposure to light.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Supplier Images
Image no. 1 for anti-CD58 Molecule (CD58) antibody (Biotin) (ABIN94196) Surface staining of human peripheral blood cells with anti-CD58 (MEM-63) FITC.