SRC antibody (V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian))

Details for Product anti-SRC Antibody No. ABIN967081
Target
Reactivity
Human, Mouse, Rat
308
195
165
19
13
12
12
9
9
5
5
5
4
3
3
1
1
1
1
Host
Rabbit
288
39
1
Clonality
Polyclonal
Conjugate
This SRC antibody is un-conjugated
23
17
16
12
12
11
9
6
6
6
6
6
3
3
3
3
3
1
1
Application
Immunohistochemistry (IHC)
252
159
115
48
40
30
25
19
11
8
7
4
3
2
1
Options
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human Src around the phosphorylation site of tyrosine 418 (N-E-YP-T-A).
Specificity Src (Ab-418) antibody detects endogenous levels of total Src protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Target
Alternative Name Src (SRC Antibody Abstract)
Pathways JAK-STAT Signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
Application Notes WB: 1:500~1:1000.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: David-Dufilho, Millanvoye-Van Brussel, Topal, Walch, Brunet, Rendu: "Endothelial thrombomodulin induces Ca2+ signals and nitric oxide synthesis through epidermal growth factor receptor kinase and calmodulin kinase II." in: The Journal of biological chemistry, Vol. 280, Issue 43, pp. 35999-6006, 2005 (PubMed).

Sanders, Basson: "p130cas but not paxillin is essential for Caco-2 intestinal epithelial cell spreading and migration on collagen IV." in: The Journal of biological chemistry, Vol. 280, Issue 25, pp. 23516-22, 2005 (PubMed).

Murugappan, Shankar, Bhamidipati, Dorsam, Jin, Kunapuli: "Molecular mechanism and functional implications of thrombin-mediated tyrosine phosphorylation of PKCdelta in platelets." in: Blood, Vol. 106, Issue 2, pp. 550-7, 2005 (PubMed).

Gu, Santiago, Mitchell: "Synergy between imatinib and mycophenolic acid in inducing apoptosis in cell lines expressing Bcr-Abl." in: Blood, Vol. 105, Issue 8, pp. 3270-7, 2005 (PubMed).

Zhou, Schmelz, Seufferlein, Li, Zhao, Bachem: "Molecular mechanisms of low intensity pulsed ultrasound in human skin fibroblasts." in: The Journal of biological chemistry, Vol. 279, Issue 52, pp. 54463-9, 2004 (PubMed).