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Myelin Basic Protein (MBP) antibody Primary Antibody

MBP Reactivity: Human ICC, FACS, IHC, ELISA, WB Host: Mouse Monoclonal 2H9 unconjugated
Pubmed (2)
Catalog No. ABIN969279
$448.80
Plus shipping costs $45.00
100 μL
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  • Target
    Myelin Basic Protein (MBP)
    Reactivity
    • 139
    • 47
    • 37
    • 35
    • 17
    • 16
    • 12
    • 12
    • 9
    • 8
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 91
    • 48
    • 13
    • 10
    • 1
    • 1
    • 1
    Mouse
    Clonality
    • 101
    • 63
    Monoclonal
    Conjugate
    • 118
    • 9
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Un-conjugated
    Application
    • 98
    • 71
    • 50
    • 23
    • 22
    • 20
    • 15
    • 14
    • 12
    • 10
    • 9
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Purification
    Ascites
    Immunogen
    Purified recombinant fragment of human MBP expressed in E. Coli.
    Clone
    2H9
    Isotype
    IgG1
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Rajaraman, Brenner, Butler, Wang, Pfeiffer, Ruder, Linet, Yeager, Wang, Orr, Fine, Kwon, Thomas, Rothman, Inskip, Chanock: "Common variation in genes related to innate immunity and risk of adult glioma." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 5, pp. 1651-8, 2009 (PubMed).

    Hoos, Ahmed, Smith, Van Nostrand: "Myelin basic protein binds to and inhibits the fibrillar assembly of Abeta42 in vitro." in: Biochemistry, Vol. 48, Issue 22, pp. 4720-7, 2009 (PubMed).

  • Target
    Myelin Basic Protein (MBP)
    Alternative Name
    Myelin basic protein (MBP Antibody Abstract)
    Synonyms
    C76307, Hmbpr, R75289, golli-mbp, mld, shi, Mbps, cb274, fj33b11, mbp, wu:fj33b11, wu:fq15b02, zgc:136630, MGC115135, myelin basic protein, myelin basic protein a, myelin basic protein L homeolog, MBP, Mbp, mbpa, mbp, mbp.L
    Background
    The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes.
    Molecular Weight
    33 kDa
    Gene ID
    4155
    HGNC
    4155
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