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FGA antibody

FGA Reactivity: Human WB, IHC, ELISA Host: Goat Polyclonal unconjugated
Rockland
Catalog No. ABIN99199
Supplier Product No.: 100-101-240
  • Target See all FGA Antibodies
    FGA (Fibrinogen alpha Chain (FGA))
    Reactivity
    • 48
    • 35
    • 25
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 59
    • 17
    • 5
    • 2
    Goat
    Clonality
    • 64
    • 19
    Polyclonal
    Conjugate
    • 43
    • 11
    • 9
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FGA antibody is un-conjugated
    Application
    • 64
    • 29
    • 25
    • 13
    • 13
    • 10
    • 10
    • 9
    • 9
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Supplier Product No.
    100-101-240
    Supplier
    Rockland
    Purpose
    Fibrinogen Antibody
    Cross-Reactivity (Details)
    Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-goat serum, purified and partially purified Fibrinogen [Human Plasma].
    Characteristics
    Synonyms: goat anti-Fibrinogen Antibody, FGA antibody, FGA protein antibody, FGB antibody, FGG antibody, Fib2 antibody, Fibrinogen A alpha polypeptide antibody, Fibrinogen A alpha polypeptide chain antibody, Fibrinogen alpha chain antibody
    Purification
    This product was prepared from monospecific antiserum by a delipidation and defibrination.
    Immunogen

    Immunogen: Fibrinogen [Human Plasma]

    Immunogen Type: Native Protein

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    Discover our top product FGA Primary Antibody
  • Application Notes

    Immunohistochemistry Dilution: 1:500

    Application Note: Anti-Fibrinogen has been tested by western blot and immunohistochemistry and is suitable to be assayed against 1.0 μg of Fibrinogen [Human Plasma] in a standard ELISA using Peroxidase conjugated Affinity Purified anti-Goat IgG [H&L] (Rabbit) code #605-4302 and (ABTS (2,2'-azino-bis-[3-ethylbenthiazoline-6-sulfonic acid]) code # ABTS-100 as a substrate for 30 minutes at room temperature.  A working dilution of 1:10,000 to 1:50,000 of the reconstitution concentration is suggested for this product.

    Western Blot Dilution: 1:2,000 - 1:10,000

    ELISA Dilution: 1:20,000 - 1:100,000

    Other: User Optimized

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution

    Reconstitution Volume: 2.0 mL

    Reconstitution Buffer: Restore with deionized water (or equivalent)

    Concentration
    90 mg/mL
    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    Expiry Date
    12 months
  • Target
    FGA (Fibrinogen alpha Chain (FGA))
    Alternative Name
    FGA (FGA Products)
    Background
    Background: Fibrinogen is cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA), fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, it functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. It was originally thought to be essential for platelet aggregation, based on in vitro studies using anti-coagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. It enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. It may also facilitate the immune response via both innate and T-cell mediated pathways.
    Gene ID
    2243
    NCBI Accession
    NP_000499
    UniProt
    P02671
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