FGA Products
(Fibrinogen alpha Chain (FGA))
Categories
The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq, Jul 2008].
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Featured FGA Categories
FGA Antibodies
High quality antibodies with extensive validation data.
FGA ELISA Kits
Reliable ELISA kits for a wide range of species.
FGA Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FGA Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, ICC, IHC (p), IHC (fro)
Validations
- (5)
Cat. No.
ABIN7433189
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7443677
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IP, PLA
Validations
- (5)
Cat. No.
ABIN515603
Quantity
100 μg
Datasheet
Datasheet
Recommended FGA ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (4)
Cat. No.
ABIN6574256
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6955777
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966736
Quantity
96 tests
Datasheet
Datasheet
Recommended FGA Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1353978
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3131128
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505542
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our FGA products
: "Comparative Proteomics Analysis of Serum Proteins in Gestational Diabetes during Early and Middle Stages of Pregnancy." in: Proteomics. Clinical applications, Vol. 13, Issue 5, pp. e1800060, (2020) (PubMed).: "Breaking the vicious loop between inflammation, oxidative stress and coagulation, a novel anti-thrombus insight of nattokinase by inhibiting LPS-induced inflammation and oxidative stress." in: Redox biology, Vol. 32, pp. 101500, (2020) (PubMed).
: "Nattokinase-heparin exhibits beneficial efficacy and safety-an optimal strategy for CKD patients on hemodialysis." in: Glycoconjugate journal, Vol. 36, Issue 2, pp. 93-101, (2019) (PubMed).
: "An efficient system for secretory production of fibrinogen using a hepatocellular carcinoma cell line." in: Hepatology research : the official journal of the Japan Society of Hepatology, Vol. 45, Issue 3, pp. 315-25, (2016) (PubMed).
: "Near-Infrared Emitting PbS Quantum Dots for in Vivo Fluorescence Imaging of the Thrombotic State in Septic Mouse Brain." in: Molecules (Basel, Switzerland), Vol. 21, Issue 8, (2016) (PubMed).
: "Comparative analysis of the serum proteome for biomarker discovery to reveal hepatotoxicity induced by iron ion radiation in mice." in: Life sciences, Vol. 167, pp. 57-66, (2016) (PubMed).
: "Dispersing carbon nanotubes by chiral network surfactants." in: ACS applied materials & interfaces, Vol. 7, Issue 12, pp. 6724-32, (2015) (PubMed).
: "Cocktail blood biomarkers: prediction of clinical outcomes in patients with acute ischemic stroke." in: European neurology, Vol. 69, Issue 2, pp. 68-75, (2013) (PubMed).
: "Differences of circulating inflammatory markers between large- and small vessel disease in patients with acute ischemic stroke." in: International journal of medical sciences, Vol. 10, Issue 10, pp. 1399-405, (2013) (PubMed).
: "Mast cell restricted mouse and human tryptase·heparin complexes hinder thrombin-induced coagulation of plasma and the generation of fibrin by proteolytically destroying fibrinogen." in: The Journal of biological chemistry, Vol. 287, Issue 11, pp. 7834-44, (2012) (PubMed).
Synonyms and alternative names related to FGA
fibrinogen alpha chain (FGA), fibrinogen alpha chain (Fga), fibrinogen alpha chain (LOC698244), Ac1873, ENSMUSG00000059807, Fba5e, Fib, Fib2Protein level used designations for FGA
- fibrinogen alpha chain
- fibrinogen alpha chain-like
- fibrinogen, A alpha polypeptide
- fibrinogen A-alpha chain
- fibrinogen, alpha polypeptide
- carboxy-terminal region
- fibrinogen A-alpha-chain
- fibrinogen alpha subunit
- fibrinogen alpha-E subunit
- pre-fibrinogen alpha subunit
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