Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Human BAK1 Antibodies:
anti-Mouse (Murine) BAK1 Antibodies:
anti-Rat (Rattus) BAK1 Antibodies:
Go to our pre-filtered search.
Human Monoclonal BAK1 Primary Antibody for WB - ABIN967519
Chittenden, Harrington, OConnor, Flemington, Lutz, Evan, Guild: Induction of apoptosis by the Bcl-2 homologue Bak. in Nature 1995
Show all 4 Pubmed References
Human Polyclonal BAK1 Primary Antibody for IHC (p), WB - ABIN967522
Krajewska, Moss, Krajewski, Song, Holt, Reed: Elevated expression of Bcl-X and reduced Bak in primary colorectal adenocarcinomas. in Cancer research 1996
Show all 3 Pubmed References
Human Polyclonal BAK1 Primary Antibody for IHC, ELISA - ABIN1533215
Plötz, Gillissen, Hossini, Daniel, Eberle: Disruption of the VDAC2-Bak interaction by Bcl-x(S) mediates efficient induction of apoptosis in melanoma cells. in Cell death and differentiation 2012
Show all 2 Pubmed References
Human Polyclonal BAK1 Primary Antibody for IF (p), IHC (p) - ABIN674409
Zhu, Wang, Liang, Wang, Zhang, Li, Ying: Regulation of cell transformation by Rb-controlled redox homeostasis. in PLoS ONE 2014
Show all 2 Pubmed References
Human Polyclonal BAK1 Primary Antibody for WB - ABIN2801911
Farrow, White, Martinou, Raven, Pun, Grinham, Martinou, Brown: Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K. in Nature 1995
Human Polyclonal BAK1 Primary Antibody for IHC, IHC (p) - ABIN4282996
Krajewska, Rosenthal, Mikolajczyk, Stennicke, Wiesenthal, Mai, Naito, Salvesen, Reed, Fiskum, Krajewski: Early processing of Bid and caspase-6, -8, -10, -14 in the canine brain during cardiac arrest and resuscitation. in Experimental neurology 2004
Human Polyclonal BAK1 Primary Antibody for ELISA, WB - ABIN257856
Derry, Ochs, Francke: Isolation of a novel gene mutated in Wiskott-Aldrich syndrome. in Cell 1994
The role of BAK1 in defense against root-knot (show KCNK7 Antibodies) nematode and pattern-triggered immunity
N-glycosylation and specific ERQC components are essential to activate bak1/serk4 cell death, and CRK4 is likely to be among client proteins of protein glycosylation involved in BAK1/SERK4-regulated cell death.
BAK1 and SOBIR1 associate with each other in planta when the function of BIR1 (show KCNJ6 Antibodies) is compromised.
an allosteric mechanism for inhibition of BAK1 by C408 S-glutathionylation
Study identifies a link between plant perception of biotic threats by BAK1, cellular calcium entry mediated by GLRs, and intracellular calcium release by TPC1 (show TPCN1 Antibodies) during a biologically relevant interaction.
The Arabidopsis Malectin (show MLEC Antibodies)-Like/LRR-RLK (show TXK Antibodies) IOS1 Is Critical for BAK1-Dependent and BAK1-Independent Pattern-Triggered Immunity
These findings show that BAK1 contains an additional AtRALF1 binding site, indicating that this protein may be part of a AtRALF1-containing complex as a co-receptor, and it is required for the negative regulation of cell expansion
the existence of partial redundancy between SERK3 and SERK1 as well as the promoting or repressive activity of a single coreceptor in multiple simultaneously active pathways, is reported.
The found that in an otherwise "active" BAK1 the alphaC helix is highly disordered, a hallmark of deactivation, whereas the BRI1 alphaC helix is moderately disordered and displays swinging behavior similar to numerous animal kinases.
These data suggest that BIK1 cooperates with BAK1 to regulate constitutive immunity and cell death.
interleukin-6 (show IL6 Antibodies), endothelin ET-1 (show EDN1 Antibodies), and apoptotic Bak and Bcl-XL (show BCL2L1 Antibodies) genes have roles in small bowel transplantation, in a swine model of ischemia and reperfusion injury
Bak mRNA was significantly increased in haploid parthenotes compared with the diploid parthenotes. These results suggest that the haploid state affects apoptosis-related gene expression which results in increased apoptosis
This comprehensive survey showed that in each Bak dimer the N-termini are fully solvent-exposed and mobile, the core is highly structured, and the C-termini are flexible but restrained by their contact with the membrane.
The BAK1/BCL2 (show BCL2 Antibodies) ratio was positively correlated with the results of audiometric tests. Our results indicate that BAK-mediated apoptosis may be a core mechanism in the progression of age-related hearing impairment in humans
UMI-77 enhances TRAIL-induced apoptosis by unsequestering Bim (show BCL2L11 Antibodies) and Bak, which provides a novel therapeutic strategy for the treatment of gliomas.
after the induction of apoptosis, Bak switches from its association with Mtx2 (show MTX2 Antibodies) and VDAC2 (show VDAC2 Antibodies) to a closer association with Mtx1 (show MTX1 Antibodies).
Conversion of Bim (show BCL2L11 Antibodies)-BH3 from Activator to Inhibitor of Bak through Structure-Based Design.
The results strongly suggest that the direct apoptosis-activation activities of Bid (show BID Antibodies), Bim (show BCL2L11 Antibodies), Puma (show BBC3 Antibodies), and p53 (show TP53 Antibodies) are not essential for activating Bax (show BAX Antibodies)/Bak once the anti-apoptotic Bcl-2 (show BCL2 Antibodies) proteins are neutralized.
Studied BAK1, SPRY4 (show SPRY4 Antibodies) and GAB2 (show GAB2 Antibodies) SNPs in pediatric germ cell tumors(GCT (show QPCT Antibodies)); found a variant in SPRY4 (show SPRY4 Antibodies) was associated with reduced risk of GCT (show QPCT Antibodies); a variant in BAK1 was positively associated with GCT (show QPCT Antibodies) with a strong estimated effect for testis tumors; and a SNP in GAB2 (show GAB2 Antibodies) was associated with increased risk for GCT (show QPCT Antibodies).
These results not only establish Bok (show BOK Antibodies) as a Bak- and Bax (show BAX Antibodies)-independent apoptosis inducer, but also suggest a potential impact of Bok (show BOK Antibodies) expression in ovarian cancer therapy.
The low-level constitutive production of platelets caused by the G allele of rs5745568 in BAK1 protein seems to increase the risk of bleeding in dengue infection
the expression of Bak1 was downregulated in CRC (show CALR Antibodies) tumor tissues and was reversely correlated with the expression of miR410, which provided further support that Bak1 was regulated by miR410.
We propose that the GC-induced mitochondrial accumulation of Bax (show BAX Antibodies) and the interaction between the GR and Bim (show BCL2L11 Antibodies), Bcl-xL (show BCL2L1 Antibodies) and Bak could play a role in the regulation of thymocyte apoptosis.
Postnatal synaptic rearrangement needed for acquisition of skilled behaviors requires the activity-dependent, non-apoptotic Bax (show BAX Antibodies)/Bak-caspase (show CASP3 Antibodies) signaling cascade. Adult Bax (show BAX Antibodies)/Bak mutant mice exhibit aberrant co-activation of antagonistic muscle pairs and skilled grasping deficits but normal reaching and retrieval behaviors.
The authors show that Bak is activated and that activated Bak is bound to p53 (show TP53 Antibodies) during reovirus encephalitis.
Pancreatic beta-Cell Death due to Pdx-1 (show PDX1 Antibodies) Deficiency Requires Multi-BH Domain Protein Bax (show BAX Antibodies) but Not Bak.
lipid profile in the absence of the proapoptotic proteins BAX (show BAX Antibodies) and BAK in mouse embryonic fibroblasts
alpha1 dissociation is a key step in unfolding Bak into three major components, the N terminus, the core (alpha2-alpha5) and the latch (alpha6-alpha8) that is required for apoptosis.
BAX (show BAX Antibodies) and BAK have a nonapoptotic role in eicosanoid metabolism in inflammation.
Puma (show BBC3 Antibodies) is the major mediator of virus-induced Bax (show BAX Antibodies)/Bak activation and mitochondrial membrane permeabilization induction.
Motifs of VDAC2 (show VDAC2 Antibodies) required for mitochondrial Bak import and tBid-induced apoptosis.
regulation of A1 and Bak contribute to mitochondrial membrane stability, reduced caspase-9 (show CASP9 Antibodies) activity, and delayed apoptosis in bovine neutrophils exposed to glucocorticoids
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
BCL2-like 7 protein
, apoptosis regulator BAK
, bcl-2 homologous antagonist/killer
, bcl-2-like protein 7
, pro-apoptotic protein BAK
, Bcl2 homologous antagonist/killer
, Bcl-2-like 7