anti-DFFB Antibodies
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anti-DFFB antibody (DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase)) (AA 1-30) Primary Antibody
anti-DFFB antibody (DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase)) (N-Term) Primary Antibody
anti-DFFB antibody (DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase)) (Internal Region) Primary Antibody
anti-DFFB antibody (DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase)) (Internal Region) Primary Antibody
anti-DFFB antibody (DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase)) (Middle Region) Primary Antibody
anti-DFFB antibody (DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase)) (AA 229-338) Primary Antibody
anti-DFFB antibody (DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase)) (AA 205-222) Primary Antibody
anti-DFFB antibody (DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase)) (AA 1-338) Primary Antibody
anti-DFFB antibody (DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase)) (AA 205-222) Primary Antibody
anti-DFFB antibody (DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase)) (N-Term) Primary Antibody
DFFB Antigen Profile
Protein Summary
Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene but the biological validity of these variants has not been determined.
Alternative names and synonyms associated with DFFB
- DNA fragmentation factor subunit beta (DFFB) antibody
- DNA fragmentation factor subunit beta (LOC100223514) antibody
- DNA fragmentation factor subunit beta (Dffb) antibody
- DNA fragmentation factor, beta subunit (Dffb) antibody
- 40kDa antibody
- 5730477D02Rik antibody
- Cad antibody
- CPAN antibody
- DFF-40 antibody
- DFF2 antibody
- DFF40 antibody
- Didff antibody
- LOC100223514 antibody
Protein level used designations for DFFB
DNA fragmentation factor subunit beta , DNA fragmentation factor, 40 kD, beta polypeptide , DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) , DNA fragmentation factor 40 kDa subunit , caspase-activated DNase , caspase-activated deoxyribonuclease , caspase-activated nuclease , DFF-40 , DNA fragmentation factor 40 kD beta polypeptide (caspase-activated DNase) , DNA fragmentation factor, 40 kD, beta polypeptide (caspase-activated DNase) , DNA fragmentation factor, beta polypeptide (caspase-activated DNase) , DNA fragmentation factor, beta subunit , DNA fragmentation factor, 40 kD, beta subunit , DNase inhibited by DNA fragmentation factor
| GENE ID | SPECIES |
|---|---|
| 374158 | Gallus gallus |
| 744932 | Pan troglodytes |
| 100223514 | Taeniopygia guttata |
| 1677 | Homo sapiens |
| 84359 | Rattus norvegicus |
| 100713108 | Cavia porcellus |
| 512730 | Bos taurus |
| 489623 | Canis lupus familiaris |
| 13368 | Mus musculus |
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