NAIP Proteins

Protein Summary

This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length\; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alternative names and synonyms associated with NAIP

• NLR family apoptosis inhibitory protein (NAIP) antibody
• NLR family, apoptosis inhibitory protein 1 (Naip1) antibody

• AV364616 antibody
• BIRC1 antibody
• Birc1a antibody
• D13Lsd1 antibody
• Naip antibody
• Show all synonym aliases
• Naip-rs1 antibody
• NLRB1 antibody
• psiNAIP antibody

Protein level used designations for NAIP

baculoviral IAP repeat-containing protein 1 , neuronal apoptosis inhibitory protein , nucleotide-binding oligomerization domain, leucine rich repeat and BIR domain containing 1 , psi neuronal apoptosis inhibitory protein , baculoviral IAP repeat-containing 1 , baculoviral IAP repeat-containing 1a , baculoviral IAP repeat-containing protein 1a , neuronal apoptosis inhibitory protein 1