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Full name:: Tumor Necrosis Factor (Ligand) Superfamily, Member 10 Proteins (TNFSF10)

On www.antibodies-online.com are 80 Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) Proteins from 20 different suppliers available. Additionally we are shipping TNFSF10 Antibodies (390) and TNFSF10 Kits (91) and many more products for this protein. A total of 580 TNFSF10 products are currently listed.

Synonyms:: A330042I21Rik, AI448571, apo-2l, apo2l, cd253, Ly81, tl2, tnfsf10l2, TNLG6A, trail, trail1, xtrail1, zgc:92320

list all proteins	Gene Name	GeneID	UniProt
	TNFSF10	8743	P50591
	TNFSF10	22035	P50592
	TNFSF10	246775
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Top referenced TNFSF10 Proteins

Human TNFSF10 Protein expressed in Wheat germ - ABIN1323209 : Borbone, De Rosa, Siciliano, Altucci, Croce, Fusco: Up-regulation of miR-146b and down-regulation of miR-200b contribute to the cytotoxic effect of histone deacetylase inhibitors on ras-transformed thyroid cells. in The Journal of clinical endocrinology and metabolism 2013 (PubMed)

More Proteins for TNFSF10 Interaction Partners

Human Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) interaction partners

Mouse (Murine) Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) interaction partners

Pig (Porcine) Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) interaction partners

Xenopus laevis Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) interaction partners

TNFSF10 Protein Profile

Protein Summary

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with TNFSF10

TNF superfamily member 10 (TNFSF10)
tumor necrosis factor (ligand) superfamily, member 10 (Tnfsf10)
TNF superfamily member 10 (Tnfsf10)
tumor necrosis factor superfamily member 10 (TNFSF10)
TNF superfamily member 10 S homeolog (tnfsf10.S)
TNF superfamily member 10 (tnfsf10)

A330042I21Rik protein
AI448571 protein
apo-2l protein
apo2l protein
cd253 protein
Ly81 protein
tl2 protein
tnfsf10l2 protein
TNLG6A protein
trail protein
trail1 protein
xtrail1 protein
zgc:92320 protein

Protein level used designations for TNFSF10

Apo-2 ligand , TNF-related apoptosis inducing ligand TRAIL , chemokine tumor necrosis factor ligand superfamily member 10 , tumor necrosis factor (ligand) family, member 10 , tumor necrosis factor apoptosis-inducing ligand splice variant delta , tumor necrosis factor ligand superfamily member 10 , TNF-related apoptosis inducing ligand , TNF-related apoptosis-inducing ligand , TRAIL/APO2L , tumor necrosis factor-related apoptosis-inducing ligand , TNF-related apoptosis-inducing ligand 1 , tumor necrosis factor related apoptosis inducing ligand 1 , DL2 , TNFSF10-1 , tumor necrosis factor (ligand) superfamily, member 10 like 2 , tumor necrosis factor (ligand) superfamily, member 10 , tumor necrosis factor ligand 6A , tumor necrosis factor superfamily member 10

GENE ID	SPECIES
8743	Homo sapiens
22035	Mus musculus
246775	Rattus norvegicus
378894	Gallus gallus
406191	Sus scrofa
100174780	Canis lupus familiaris
100174789	Felis catus
100316914	Xenopus laevis
436866	Danio rerio
694451	Macaca mulatta

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