Browse our anti-LAMP2 (LAMP2) Antibodies

Full name:: anti-Lysosomal-Associated Membrane Protein 2 Antibodies (LAMP2)

On www.antibodies-online.com are 427 Lysosomal-Associated Membrane Protein 2 (LAMP2) Antibodies from 31 different suppliers available. Additionally we are shipping LAMP2 Proteins (25) and LAMP2 Kits (19) and many more products for this protein. A total of 484 LAMP2 products are currently listed.

Synonyms:: cd107b, DKFZp459J126, lamp-2, Lamp-2a, Lamp-2b, Lamp-2c, lamp2, lampb, LGP-B, LGP110, Mac3, sb:cb587, wu:fb14a06, zgc:103532

list all antibodies	Gene Name	GeneID	UniProt
	LAMP2	3920	P13473
	LAMP2	16784	P17047
	LAMP2	24944
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Relevant Pathways for anti-LAMP2 Antibodies

Autophagy

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Top referenced anti-LAMP2 Antibodies

Human Monoclonal LAMP2 Primary Antibody for CyTOF, FACS - ABIN4330233 : Nishino, Fu, Tanji, Yamada, Shimojo, Koori, Mora, Riggs, Oh, Koga, Sue, Yamamoto, Murakami, Shanske, Byrne, Bonilla, Nonaka, DiMauro, Hirano: Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease). in Nature 2000 (PubMed)
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Human Monoclonal LAMP2 Primary Antibody for FACS, ICC - ABIN638447 : Denzer, van Eijk, Kleijmeer, Jakobson, de Groot, Geuze: Follicular dendritic cells carry MHC class II-expressing microvesicles at their surface. in Journal of immunology (Baltimore, Md. : 1950) 2000 (PubMed)
Show all 8 Pubmed References
Human Monoclonal LAMP2 Primary Antibody for IHC (f), ICC - ABIN2749100 : Palmer, Fernandez, Bisbing, Peachman, Rao, Barvir, Gunther, Burgess, Kohno, Padmanabhan, Sun: Restricted replication and lysosomal trafficking of yellow fever 17D vaccine virus in human dendritic cells. in The Journal of general virology 2006 (PubMed)
Show all 7 Pubmed References
Human Monoclonal LAMP2 Primary Antibody for IHC (f), ICC - ABIN2749101 : Meade, Wilson, Holmes, de Wynter, Brett, Straszynski, Ballard, Trapani, McDermott, Cook: Proteolytic activation of the cytotoxic phenotype during human NK cell development. in Journal of immunology (Baltimore, Md. : 1950) 2009 (PubMed)
Show all 7 Pubmed References
Mouse (Murine) Monoclonal LAMP2 Primary Antibody for FACS, IHC (fro) - ABIN262473 : Bai, Li, Zhang, Matkowskyj, Liao, Srivastava, Yang: Inhibition of chronic pancreatitis and pancreatic intraepithelial neoplasia (PanIN) by capsaicin in LSL-KrasG12D/Pdx1-Cre mice. in Carcinogenesis 2011 (PubMed)
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Mouse (Murine) Monoclonal LAMP2 Primary Antibody for IHC (f), IHC (fro) - ABIN2688887 : Chen, Murphy, Willingham, Pastan, August: Identification of two lysosomal membrane glycoproteins. in The Journal of cell biology 1985 (PubMed)
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Human Polyclonal LAMP2 Primary Antibody for FACS, IF (p) - ABIN680198 : Zhang, Fu, Sheng, Li, Song, Li, Song, Wang, Chen, Yu, Wei: Bone marrow CD11b(+)F4/80(+) dendritic cells ameliorate collagen-induced arthritis through modulating the balance between Treg and Th17. in International immunopharmacology 2015 (PubMed)
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Human Monoclonal LAMP2 Primary Antibody for IHC (f), ICC - ABIN1027702 : Guia, Cognet, de Beaucoudrey, Tessmer, Jouanguy, Berger, Filipe-Santos, Feinberg, Camcioglu, Levy, Al Jumaah, Al-Hajjar, Stephan, Fieschi, Abel, Brossay, Casanova, Vivier: A role for interleukin-12/23 in the maturation of human natural killer and CD56+ T cells in vivo. in Blood 2008 (PubMed)
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Mouse (Murine) Monoclonal LAMP2 Primary Antibody for IHC (fro), FACS - ABIN2688888 : Walker, Akporiaye, Warner, Stewart: Characterization of subsets of bone marrow-derived macrophages by flow cytometry analysis. in Journal of leukocyte biology 1985 (PubMed)
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Human Polyclonal LAMP2 Primary Antibody for ICC, IF - ABIN152746 : Xia, de Queiroz, Sriramula, Feng, Johnson, Mungrue, Lazartigues: Brain ACE2 overexpression reduces DOCA-salt hypertension independently of endoplasmic reticulum stress. in American journal of physiology. Regulatory, integrative and comparative physiology 2015 (PubMed)
Show all 3 Pubmed References

More Antibodies against LAMP2 Interaction Partners

Human Lysosomal-Associated Membrane Protein 2 (LAMP2) interaction partners

GnT-IVa (show MGAT4A Antibodies) may contribute to the malignancy of choriocarcinoma by promoting cell adhesion, migration and invasion through glycosylation of integrin beta1 and LAMP-2.
Since effective regimens are readily available timely psychiatric evaluation is warranted in all newly diagnosed subjects with LAMP2 mutations, regardless of whether they show the typical Danon disease medical (cardiac) symptoms or not.
The authors show here that human LAMP1 (show LAMP1 Antibodies) and LAMP2 bind cholesterol in a manner that buries the cholesterol 3beta-hydroxyl group; they also bind tightly to NPC1 (show NPC1 Antibodies) and NPC2 (show NPC2 Antibodies) proteins that export cholesterol from lysosomes.
identified LAMP-2 as an endocytic receptor on monocyte-derived dendritic cells (MoDC) that routes cargo into unusual Ag processing pathways, which reduces surface expression of Ag-derived peptides while selectively enriching Ag within immunogenic exosome; this novel pathway has implications for the initiation of immune responses both locally and at distant sites
downregulation of FUT1 (show FUT1 Antibodies), which leads to the perinuclear localization of LAMP-1 (show LAMP1 Antibodies) and 2, is correlated with increased rate of autophagic flux by decreasing mTOR (show FRAP1 Antibodies) signaling and increasing autolysosome formation.
The results provide a new insight that LAMP-2 contributes to the ROS (show ROS1 Antibodies) clearance and cell death induced by Zn(2+) treatment, which would help us to get a better understanding of Zn(2+)-induced toxicity in respiratory system.
Genetic analysis identified 2 novel LAMP2 gene mutations. In Family A, a G-A transition (c.962G > A) leading to a nonsense mutation at codon 321 (p.Trp321Ter), and in Family B, a one-nucleotide insertion (c.973insC) leading to a full frame-shift (p.Pro324+24X) was detected in exon 8 of the LAMP2 gene.
the assembly modes of LAMP-1 (show LAMP1 Antibodies) and LAMP-2 are different, which may underlie their distinct functions
intracellular Salmonella recruit the host proteins LAMP-2A and Hsc73 (show HSPA8 Antibodies), key components of the host protein turnover pathway known as chaperone-mediated autophagy involved in transport of cytosolic proteins to the lysosome for degradation.
3 novel nonsense mutations (p.Q240X, p.S250X, and p.G22X) were found in LAMP2 associated with early onset Danon disease with hypertrophic cardiomyopathy. LAMP2 expression was absent in both cardiac and skeletal muscle samples of the first proband and severely decreased LAMP2 expression in the skeletal muscle samples of the second proband.

Mouse (Murine) Lysosomal-Associated Membrane Protein 2 (LAMP2) interaction partners

The results presented here show the major role of LAMP-2 in caveolin traffic and membrane repair and consequently in T. cruzi invasion.
The up-regulation of Rab11 (show RAB11A Antibodies), Rab7 (show RAB7A Antibodies), or RILP (show RILP Antibodies), but not its truncated form RILP (show RILP Antibodies)-C33 (show CD82 Antibodies), rescued LAMP2A-defective trafficking in cystinosis, whereas dominant-negative Rab11 (show RAB11A Antibodies) or Rab7 (show RAB7A Antibodies) impaired LAMP2A trafficking.
LAMP-2 in the central nervous system has a possible role in the degradation of the various macromolecules in lysosomes and an additional function concerning protection from oxidative stress, especially in the substantia nigra.
The absence of LAMP-2 in murine brain led to inflammation and abnormal behavior, including motor deficits and impaired learning.
Lamp-2 deficiency prevents high-fat diet-induced obese diabetes via enhancing energy expenditure.
These results suggest that VPS35 deficiency or mutation promotes Parkinson Disease (PD) pathogenesis, and reveals a crucial pathway, VPS35-Lamp2a-alpha-synuclein, to prevent PD pathogenesis.
LAMP proteins retain TAPL (show ABCB9 Antibodies) on the limiting membrane of endosomes and prevent its sorting to intraluminal vesicles.
Restoration of lysosome-associated membrane protein-2 levels synergizes with partial BECLIN-1 (show BECN1 Antibodies) knockdown to restore autophagosome processing and to attenuate cell death after hypoxia-reoxygenation.
results suggest that LAMP-2, its luminal domain in particular, plays a critical role in endosomal cholesterol transport and that this is distinct from the chaperone-mediated autophagy function of LAMP-2
Using LAMP1 (show LAMP1 Antibodies)/2 knock out cells the authors show that these two proteins are important for Trypanosoma cruzi infection of host cells, both in entrance and intracellular development, conceivably by being the major source of sialic acid for Trypanosoma cruzi.

LAMP2 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins.

Alternative names and synonyms associated with LAMP2

lysosomal associated membrane protein 2 (LAMP2) antibody
lysosomal-associated membrane protein 2 (Lamp2) antibody
lysosomal-associated membrane protein 2 S homeolog (lamp2.S) antibody
lysosomal-associated membrane protein 2 (lamp2) antibody
lysosomal membrane glycoprotein 2 (lamp2) antibody
lysosomal-associated membrane protein 2 (LAMP2) antibody
lysosomal associated membrane protein 2 (Lamp2) antibody

cd107b antibody
DKFZp459J126 antibody
lamp-2 antibody
Lamp-2a antibody
Lamp-2b antibody
Lamp-2c antibody
lamp2 antibody
lampb antibody
LGP-B antibody
LGP110 antibody
Mac3 antibody
sb:cb587 antibody
wu:fb14a06 antibody
zgc:103532 antibody

Protein level used designations for LAMP2

CD107 antigen-like family member B , lysosome-associated membrane glycoprotein 2 , LGP-B , Lamp II , lysosomal membrane glycoprotein 2 , lysosomal membrane glycoprotein type B , lysosome-associated membrane protein 2 , lysosome-associated membrane protein-2 , LAMP-2 , LGP-110 , LGP-96 , lysosome-associated membrane glycoprotein LAMP-2 , lysosomal-associated membrane protein 2 , Lysosome-associated membrane glycoprotein 2 , lysosome-associated membrane glycoprotein 2-like , Lysosome-associated membrane protein 2

GENE ID	SPECIES
3920	Homo sapiens
16784	Mus musculus
24944	Rattus norvegicus
414800	Gallus gallus
447742	Xenopus laevis
481037	Canis lupus familiaris
529148	Bos taurus
695379	Macaca mulatta
737597	Pan troglodytes
779509	Xenopus (Silurana) tropicalis
100154598	Sus scrofa
100169945	Felis catus
100194781	Salmo salar
100222683	Taeniopygia guttata
100398116	Callithrix jacchus
100173702	Pongo abelii
100591960	Nomascus leucogenys
100689316	Cricetulus griseus
541406	Danio rerio

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Show all anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) Antibodies with Pubmed References

Human Lysosomal-Associated Membrane Protein 2 (LAMP2) interaction partners

Mouse (Murine) Lysosomal-Associated Membrane Protein 2 (LAMP2) interaction partners

Antigen Summary

Alternative names and synonyms associated with LAMP2

Protein level used designations for LAMP2