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anti-Mouse (Murine) beta 2 Adrenergic Receptor Antibodies:
anti-Human beta 2 Adrenergic Receptor Antibodies:
anti-Rat (Rattus) beta 2 Adrenergic Receptor Antibodies:
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Human Polyclonal beta 2 Adrenergic Receptor Primary Antibody for FACS, WB - ABIN513155
Lencesova, Sirova, Csaderova, Laukova, Sulova, Kvetnansky, Krizanova: Changes and role of adrenoceptors in PC12 cells after phenylephrine administration and apoptosis induction. in Neurochemistry international 2010
Show all 2 Pubmed References
Human Polyclonal beta 2 Adrenergic Receptor Primary Antibody for FACS, IF (p) - ABIN730153
Fan, Liao, Tang, Chen, Zhang, Liu, Zhong: Role of ?2-adrenoceptor-?-arrestin2-nuclear factor-?B signal transduction pathway and intervention effects of oxymatrine in ulcerative colitis. in Chinese journal of integrative medicine 2012
Show all 2 Pubmed References
Human Monoclonal beta 2 Adrenergic Receptor Primary Antibody for Func, IA - ABIN2192080
Lebesgue, Wallukat, Mijares, Granier, Argibay, Hoebeke: An agonist-like monoclonal antibody against the human beta2-adrenoceptor. in European journal of pharmacology 1998
Show all 2 Pubmed References
Human Polyclonal beta 2 Adrenergic Receptor Primary Antibody for IHC, ELISA - ABIN1585587
Stiles, Amaya, Rains, Diaz, Pham, Battiste, Modiano, Kokta, Boucheron, Mitchell, Bryan: Targeting of beta adrenergic receptors results in therapeutic efficacy against models of hemangioendothelioma and angiosarcoma. in PLoS ONE 2013
Human Polyclonal beta 2 Adrenergic Receptor Primary Antibody for ELISA, WB - ABIN185478
Elefteriou, Ahn, Takeda, Starbuck, Yang, Liu, Kondo, Richards, Bannon, Noda, Clement, Vaisse, Karsenty: Leptin regulation of bone resorption by the sympathetic nervous system and CART. in Nature 2005
Show all 2 Pubmed References
Human Polyclonal beta 2 Adrenergic Receptor Primary Antibody for WB - ABIN2792089
Penco, Buscema, Patrosso, Marocchi, Grossi: New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background. in BMC bioinformatics 2008
Zebrafish larvae lacking beta1AR (show ADRB1 Antibodies) expression by morpholino knockdown displayed lower heart rates than control fish, whereas larvae deficient in both beta2aAR and beta2bAR expression exhibited significantly higher heart rates than controls.
the present study demonstrated that cardiac contractility/relaxation and heart rate is increased in beta1AR (show ADRB1 Antibodies) TG and beta2AR TG mice, and indicated that this increase may be related to the overexpression of G proteins and Gproteinassociated proteins.
S1928A KI mice failed to induce long-term potentiation in response to prolonged theta-tetanus (PTT-LTP (show SCP2 Antibodies)), a form of synaptic plasticity that requires Cav1.2 (show CACNA1C Antibodies) and enhancement of its activity by the beta2-adrenergic receptor (beta2AR)-cAMP-PKA cascade.
activation of beta2AR decreased cerebral amyloid plaques through the up-regulation of alpha-secretase activity and by decreasing the phosphorylation of APP (show APP Antibodies) at Thr668
Together, these data indicate that high-fat diet promotes phosphorylation of the beta2 AR, contributing to impairment of cardiac contractile reserve before cardiac structural and functional remodelling, suggesting that early intervention in the insulin (show INS Antibodies)-adrenergic signalling network might be effective in prevention of cardiac complications in diabetes
beta2-AR deletion is associated to selective hepatic insulin (show INS Antibodies) resistance and preserved skeletal muscle insulin (show INS Antibodies) sensitivity.
The diurnal variation of the humoral immune response was dependent on beta2AR-mediated neural signals and was diminished when lymphocyte recirculation through lymph nodes was stopped.
knocking out of the beta1/2 (show TFAP2B Antibodies) receptor significantly diminished the ST25 acupuncture-induced inhibition of gastric motility and jejunal motility without significantly altering the enhancement of colonic motility induced by acupuncture at ST25.
The authors show that phosphorylation of S1928 displaces the beta-2 adrenergic receptor from Cav1.2 (show CACNA1C Antibodies) upon beta-adrenergic stimulation rendering Cav1.2 (show CACNA1C Antibodies) refractory for several minutes from further beta-adrenergic stimulation.
The Galphas (show GNAS Antibodies) and Galphaq (show GNAQ Antibodies) peptides adopt different orientations in beta2-AR and V1AR (show AVPR1A Antibodies), respectively. The beta2-AR/Galphas (show GNAS Antibodies) peptide interface is dominated by electrostatic interactions, whereas the V1AR (show AVPR1A Antibodies)/Galphaq (show GNAQ Antibodies) peptide interactions are predominantly hydrophobic.
Thus the beta2AR acts as a double-edged sword: increasing TAS2R14 cell surface expression, but when activated by beta-agonist, partially offsetting the expression phenotype by direct receptor:receptor desensitization of TAS2R14 function.
These results indicate dependence of hepatic glucocorticoid and adrenergic receptors on stage of maturation in neonatal calves and emphasize the association of alpha1-adrenergic receptor and glucocorticoid receptor (show NR3C1 Antibodies) with neonatal glucose and lipid metabolism.
ADRb2 shows lipid scrambling activity.
relationship between luteal concentrations of oxytocin (OT), noradrenaline (NA), progesterone (P4), oxytocin receptors (OT-R (show OXTR Antibodies)) and beta(2)-adrenoreceptors (beta(2)-R) gene expression and their protein level throughout the estrous cycle
beta2AR signaled through Galphas (show GNAS Antibodies) and Gbetagamma subunits through a pathway that involved the tyrosine kinase (show TXK Antibodies) SRC (show SRC Antibodies), the adaptor protein SHC (show SHC1 Antibodies), the guanine nucleotide exchange factor (show RASGRF1 Antibodies) SOS, the small GTPase (show RACGAP1 Antibodies) RAS, and the kinases RAF (show RAF1 Antibodies) and MEK (show MAP2K1 Antibodies), which led to ERK (show EPHB2 Antibodies) activation
these results indicate that stimulation of the beta2AR in osteoblasts triggers a Vegf (show VEGFA Antibodies)-dependent neo-angiogenic switch that promotes bone vascular density and the colonization of the bone microenvironment by metastatic breast cancer cells.
beta2AR is linked to transcription of alpha-synuclein and risk of Parkinson's disease in a ligand-specific fashion and constitutes a potential target for therapies.
Lifetime ovulatory years were more strongly associated with ADRB2-positive ovarian tumors compared with ADRB2-negative tumors. Significant heterogeneity by ADRB2 was also observed for parity, oral contraceptive use, and age at menopause. Tumor expression of ADRB2 was not associated with ovarian cancer mortality.
ADRB2 gene polymorphism is associated with bronchodilator response in chronic obstructive pulmonary disease.
These data suggest that genetic variation of the ADRB2 may influence relative strength in healthy subjects and may become an important genetic determinant of muscular strength and functional capacity
Findings support a supramultiplicative interaction between the Gln27Glu ADRB2 variant and socioeconomic deprivation among individuals of European descent.
ADRB2 gene expressed in HIV-associated neurocognitive impairment and encephalitis chaperones OPRM1 (show OPRM1 Antibodies), normally located intracellularly in astrocytes, to the cell surface.
X ray structure of the beta2AR bound to a polyethylene glycol-carboxylic acid derivative (Cmpd-15PA)
This study demonstrates that adverse drug events induced by ritodrine are associated with ADRB2 gene polymorphisms, as well as the infusion rate of ritodrine in pregnant women with preterm labor.
A persistent B2R (show BDKRB2 Antibodies)-beta2AR heterodimer was confirmed in bradykinin-stimulated and non-stimulated left ventricular myocardium. BK transactivation of beta2AR enhanced beta2AR-mediated release of tPA (show PLAT Antibodies).
Prolactin (show PRL Antibodies) infusion brought about the inhibition of a vasodilatory beta(2)-adrenergic receptor-mediated effect related to the NO intracellular pathway
Intracoronary intermedin (show ADM2 Antibodies) 1-47 augments cardiac perfusion and function in anesthetized pigs: role of calcitonin (show CALCA Antibodies) receptors and beta-adrenoreceptor-mediated nitric oxide release.
The results imply ADRB-2-mediated actions in the development of primate follicles
This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.
adrenergic receptor beta-2
, adrenergic, beta-2-, receptor, surface
, beta-2 adrenergic receptor
, beta-2b-adrenergic receptor
, beta-2 adrenoceptor
, beta-2 adrenoreceptor
, beta 2-AR
, adrenergic receptor beta 2
, adrenergic, beta-2, receptor, surface
, catecholamine receptor
, beta2-adrenergic receptor
, Adrenergic beta 2- receptor surface
, adrenergic receptor, beta 2
, Beta-2 adrenergic receptor
, Beta-2 adrenoceptor
, Beta-2 adrenoreceptor
, beta 2 adrenergic receptor
, beta-2-adrenergic receptor