Browse our anti-beta 2 Adrenergic Receptor (ADRB2) Antibodies

Zebrafish Adrenergic, beta-2-, Receptor, Surface (ADRB2) interaction partners

1. Zebrafish larvae lacking beta1AR (show ADRB1 Antibodies) expression by morpholino knockdown displayed lower heart rates than control fish, whereas larvae deficient in both beta2aAR and beta2bAR expression exhibited significantly higher heart rates than controls.

Mouse (Murine) Adrenergic, beta-2-, Receptor, Surface (ADRB2) interaction partners

1. we identified the beta2 adrenergic receptor (ADRB2) as a downstream target for PHD3 (show EGLN3 Antibodies) in skeletal muscle

2. Here, the mechanism by which norepinephrine (NE)regulates prostate cancer DTCs in the marrow is explored. NE directly stimulated prostate cancer cell proliferation through beta2-adrenergic receptors (ADRB2).. NE also altered prostate cancer proliferation in the marrow niche by indirectly downregulating the secretion of the dormancy inducing molecule growth arrest specific-6 (GAS6 (show GAS6 Antibodies)) expressed by osteoblasts.

3. Adrenergic Receptor beta-2 signaling in the airway epithelium promotes eosinophilic inflammation, mucous metaplasia, and airway contractility.

4. the present study demonstrated that cardiac contractility/relaxation and heart rate is increased in beta1AR (show ADRB1 Antibodies) TG and beta2AR TG mice, and indicated that this increase may be related to the overexpression of G proteins and Gproteinassociated proteins.

5. S1928A KI mice failed to induce long-term potentiation in response to prolonged theta-tetanus (PTT-LTP (show SCP2 Antibodies)), a form of synaptic plasticity that requires Cav1.2 (show CACNA1C Antibodies) and enhancement of its activity by the beta2-adrenergic receptor (beta2AR)-cAMP-PKA cascade.

6. activation of beta2AR decreased cerebral amyloid plaques through the up-regulation of alpha-secretase activity and by decreasing the phosphorylation of APP (show APP Antibodies) at Thr668

7. Together, these data indicate that high-fat diet promotes phosphorylation of the beta2 AR, contributing to impairment of cardiac contractile reserve before cardiac structural and functional remodelling, suggesting that early intervention in the insulin (show INS Antibodies)-adrenergic signalling network might be effective in prevention of cardiac complications in diabetes

8. beta2-AR deletion is associated to selective hepatic insulin (show INS Antibodies) resistance and preserved skeletal muscle insulin (show INS Antibodies) sensitivity.

9. The diurnal variation of the humoral immune response was dependent on beta2AR-mediated neural signals and was diminished when lymphocyte recirculation through lymph nodes was stopped.

10. knocking out of the beta1/2 (show TFAP2B Antibodies) receptor significantly diminished the ST25 acupuncture-induced inhibition of gastric motility and jejunal motility without significantly altering the enhancement of colonic motility induced by acupuncture at ST25.

Cow (Bovine) Adrenergic, beta-2-, Receptor, Surface (ADRB2) interaction partners

1. These results indicate dependence of hepatic glucocorticoid and adrenergic receptors on stage of maturation in neonatal calves and emphasize the association of alpha1-adrenergic receptor and glucocorticoid receptor (show NR3C1 Antibodies) with neonatal glucose and lipid metabolism.

2. ADRb2 shows lipid scrambling activity.

3. relationship between luteal concentrations of oxytocin (OT), noradrenaline (NA), progesterone (P4), oxytocin receptors (OT-R (show OXTR Antibodies)) and beta(2)-adrenoreceptors (beta(2)-R) gene expression and their protein level throughout the estrous cycle

Human Adrenergic, beta-2-, Receptor, Surface (ADRB2) interaction partners

1. The authors suggest that increased circulating beta2-adrenergic receptor autoantibodies are associated with smoking-related emphysema.

2. These results suggested that adrenergic stimulation via beta1- and beta2-adrenergic receptors in the human endolymphatic sac (show ADCY10 Antibodies) was involved in regulation of inner ear fluid ion homeostasis

3. Phosphopeptide ligation onto the beta2-adrenergic receptor (beta2AR) allows stabilization of a high-affinity receptor active state by beta-arrestin1 (show ARRB1 Antibodies).

4. This study provided proof that SNPs within ADRB2 is significantly associated with the susceptibility to and the prognosis of cervical vertigo, so that NPY (show NPY Antibodies) and NA might serve as the precise diagnostic marker and treatment target of cervical vertigo.

5. A functional SNP (rs12654778), upstream of ADRB2, was significantly associated with increased risk for COPD (show ARCN1 Antibodies).

6. Data indicate clustering of beta-2 adrenergic receptor (beta2AR) variants based on their signaling profiles.

7. We found that polymorphic Arg16Gly in the ADRB2 gene and Ala54Thr in the FABP2 (show FABP2 Antibodies) gene had a discernible effect on the renal function in Chinese type 2 DN. Our data further revealed that homozygous Gly16 allele and Thr54 allele concomitantly conferred a significantly higher risk in the eGFR (show EGFR Antibodies) reduction.

8. decreased beta2AR functionality in patients with OA and LC was independent of patient's beta2AR genotype.

9. Phosphorylation of the C-terminal region of ADRB2 allosterically alters the conformation around M215(5.54) and M279(6.41), located on transemembrane helices 5 and 6.

10. Downregulation of the expression of DUSP1 or protein phosphatase 1 led to a decline in the beta2adrenergic receptormediated dephosphorylation of ERK1/2.

Pig (Porcine) Adrenergic, beta-2-, Receptor, Surface (ADRB2) interaction partners

1. The Galphas (show GNAS Antibodies) and Galphaq (show GNAQ Antibodies) peptides adopt different orientations in beta2-AR and V1AR (show AVPR1A Antibodies), respectively. The beta2-AR/Galphas (show GNAS Antibodies) peptide interface is dominated by electrostatic interactions, whereas the V1AR (show AVPR1A Antibodies)/Galphaq (show GNAQ Antibodies) peptide interactions are predominantly hydrophobic.

2. A persistent B2R (show BDKRB2 Antibodies)-beta2AR heterodimer was confirmed in bradykinin-stimulated and non-stimulated left ventricular myocardium. BK transactivation of beta2AR enhanced beta2AR-mediated release of tPA (show PLAT Antibodies).

3. Prolactin (show PRL Antibodies) infusion brought about the inhibition of a vasodilatory beta(2)-adrenergic receptor-mediated effect related to the NO intracellular pathway

4. Intracoronary intermedin (show ADM2 Antibodies) 1-47 augments cardiac perfusion and function in anesthetized pigs: role of calcitonin (show CALCA Antibodies) receptors and beta-adrenoreceptor-mediated nitric oxide release.

Rhesus Monkey Adrenergic, beta-2-, Receptor, Surface (ADRB2) interaction partners

1. The results imply ADRB-2-mediated actions in the development of primate follicles