beta 2 Adrenergic Receptor antibody (AA 302-413)
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- Target See all beta 2 Adrenergic Receptor (ADRB2) Antibodies
- beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
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Binding Specificity
- AA 302-413
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Reactivity
- Human, Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This beta 2 Adrenergic Receptor antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human ADRB2 (AA: 302-413) expressed in E. coli.
- Clone
- 5G3B5
- Isotype
- IgG1
- Top Product
- Discover our top product ADRB2 Primary Antibody
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: , ICC: , FCM: 1:200 - 1:400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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- Target
- beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
- Alternative Name
- ADRB2 (ADRB2 Products)
- Synonyms
- zgc:162188 antibody, adrb2 antibody, Adrb-2 antibody, Badm antibody, Gpcr7 antibody, ADRB2R antibody, ADRBR antibody, B2AR antibody, BAR antibody, BETA2AR antibody, adrenoceptor beta 2 antibody, adrenoceptor beta 2, surface b antibody, beta2-adrenergic receptor antibody, adrenergic receptor, beta 2 antibody, ADRB2 antibody, adrb2b antibody, LOC100136153 antibody, Adrb2 antibody
- Background
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Description: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.,
Aliases: BAR, B2AR, ADRBR, ADRB2R, BETA2AR
- Molecular Weight
- 46.5 kDa
- Gene ID
- 154
- HGNC
- 11293627
- Pathways
- cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation
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