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anti-Human CXCR2 Antibodies:
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Human Monoclonal CXCR2 Primary Antibody for CyTOF, FACS - ABIN4899080
Keane, Donnelly, Belperio, Goodman, Dy, Burdick, Fishbein, Strieter: Imbalance in the expression of CXC chemokines correlates with bronchoalveolar lavage fluid angiogenic activity and procollagen levels in acute respiratory distress syndrome. in Journal of immunology (Baltimore, Md. : 1950) 2002
Show all 30 Pubmed References
Mouse (Murine) Monoclonal CXCR2 Primary Antibody for CyTOF, FACS - ABIN4899087
Bi, Zhou, Yang, Wang, Zhang, Wang, Wu, Han, Song, Tan, Du, Yang, Zhou, Cui, Zhou, Yan, Zhang, Guo, Wang, Liu, Yang: IL-17A produced by neutrophils protects against pneumonic plague through orchestrating IFN-γ-activated macrophage programming. in Journal of immunology (Baltimore, Md. : 1950) 2014
Show all 18 Pubmed References
Mouse (Murine) Monoclonal CXCR2 Primary Antibody for FACS - ABIN4895477
Ishii, Asano, Namkoong, Tasaka, Mizoguchi, Asami, Kamata, Kimizuka, Fujiwara, Funatsu, Kagawa, Miyata, Ishii, Nakamura, Hirai, Nagata, Kunkel, Hasegawa, Betsuyaku: CRTH2 is a critical regulator of neutrophil migration and resistance to polymicrobial sepsis. in Journal of immunology (Baltimore, Md. : 1950) 2012
Show all 14 Pubmed References
Human Monoclonal CXCR2 Primary Antibody for FACS - ABIN4895454
Oo, Weston, Lalor, Curbishley, Withers, Reynolds, Shetty, Harki, Shaw, Eksteen, Hubscher, Walker, Adams: Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. in Journal of immunology (Baltimore, Md. : 1950) 2010
Show all 6 Pubmed References
Human Monoclonal CXCR2 Primary Antibody for FACS - ABIN4895450
Mihara, Smit, Krajnc-Franken, Gossen, Rooseboom, Dokter: Human CXCR2 (hCXCR2) takes over functionalities of its murine homolog in hCXCR2 knockin mice. in European journal of immunology 2005
Show all 4 Pubmed References
Mouse (Murine) Monoclonal CXCR2 Primary Antibody for FACS - ABIN4895473
Citro, Valle, Cantarelli, Mercalli, Pellegrini, Liberati, Daffonchio, Kastsiuchenka, Ruffini, Battaglia, Allegretti, Piemonti: CXCR1/2 inhibition blocks and reverses type 1 diabetes in mice. in Diabetes 2015
Show all 3 Pubmed References
Human Polyclonal CXCR2 Primary Antibody for IF (cc), IF (p) - ABIN732218
Goetzenich, Kraemer, Rossaint, Bleilevens, Dollo, Siry, Rajabi-Alampour, Beckers, Soppert, Lue, Rex, Bernhagen, Stoppe: The role of macrophage migration inhibitory factor in anesthetic-induced myocardial preconditioning. in PLoS ONE 2014
Show all 2 Pubmed References
Human Polyclonal CXCR2 Primary Antibody for CM, ICC - ABIN2749710
Sun, Ramnath, Bhatia: Neuropeptide substance P upregulates chemokine and chemokine receptor expression in primary mouse neutrophils. in American journal of physiology. Cell physiology 2007
Show all 2 Pubmed References
Human Monoclonal CXCR2 Primary Antibody for FACS - ABIN4895446
Pokkali, Das, R: Expression of CXC and CC type of chemokines and its receptors in tuberculous and non-tuberculous effusions. in Cytokine 2008
Human Monoclonal CXCR2 Primary Antibody for WB - ABIN4265500
Jayatilaka, Tyle, Chen, Kwak, Ju, Kim, Lee, Wu, Gilkes, Fan, Wirtz: Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration. in Nature communications 2017
These data were in close agreement with the reduced cell migration and colony formation. Results from the present study suggested that reparixin and SCH527123 may be promising therapeutic agents for the treatment of pancreatic cancer by inhibiting the IL8 (show IL8 Antibodies)/CXCR1 (show CXCR1 Antibodies)/2 signaling cascade.
The CXCR2 rs1126579 TT genotype had a significantly increased possibility of HCV spontaneous clearance.
increased production of IL-8 (show IL8 Antibodies) associated with neutrophils infiltration into the liver and decreased CXCR1 (show CXCR1 Antibodies)/2 expression on peripheral neutrophils. CXCR1 (show CXCR1 Antibodies) and CXCR2 expression levels could be served as early markers to predict the severity of acute-on-chronic liver failure.
CXCR2 protein expression was up-regulated in both the epileptic foci of temporal lobe epilepsy patients and in the pilocarpine mouse model. The CXCR2 selective antagonist SB225002, which was i.p. administered during the spontaneous recurrent seizures (SRSs) latency window preceding SRS (show SMS Antibodies) onset, suppressed SRSs activity during the chronic period of epilepsy.
inflammation triggered property of Microcystin-LR via IL-8 (show IL8 Antibodies)/CXCR2 signaling
results indicated that the CXCR2 +1208 CT genotype is less frequent in advanced stages of prostate cancer, suggesting that this chemokine receptor plays a role in the pathogenesis of this disease
CXCR2 expression is a promoter of CRC (show CALR Antibodies) local as well as distant metastasis and unfavorably associated with CRC (show CALR Antibodies) patients' prognosis. Moreover, CXCR2 can stratify high-risk patients especially in normally early stage low-risk CRC (show CALR Antibodies) patients.
PADI4 (show PADI4 Antibodies) contributes to gastric tumorigenesis by upregulating CXCR2, KRT14 (show KRT14 Antibodies) and TNF-alpha (show TNF Antibodies) expression.
Association of polymorphic markers of chemokine (show CCL1 Antibodies) genes, their receptors, and CD14 (show NDUFA2 Antibodies) gene with coronary atherosclerosis
In this review, we summarize the biological functions and clinical significance of the CXCL8 (show IL8 Antibodies)-CXCR1 (show CXCR1 Antibodies)/2 signaling pathway in cancer. Targeting CXCL8 (show IL8 Antibodies) or CXCR1 (show CXCR1 Antibodies)/2 may be an attractive therapeutic strategy for tumors.
Results also demonstrated that in CXCR2 (show CXCR1 Antibodies), genotypes BC, CC and FF were probably relevant with mastitis and the genotypes AA, AB and EE may have better milk quality.
TIARP (show STEAP4 Antibodies) independently down-regulated CXCL2 (show CXCL2 Antibodies) and IL-6 (show IL6 Antibodies) production by fibroblast-like synoviocytes, and the expression of chemokine (show CCL1 Antibodies) receptors (CXCR1 (show CXCR1 Antibodies) and CXCR2) in neutrophils, with resultant reduction of neutrophil migration into arthritic joints.
CXCR2 protein expression was up-regulated in both the epileptic foci of temporal lobe epilepsy patients and in the pilocarpine mouse model. The CXCR2 selective antagonist SB225002, which was i.p. administered during the spontaneous recurrent seizures (SRSs) latency window preceding SRS (show SRR Antibodies) onset, suppressed SRSs activity during the chronic period of epilepsy.
these data provide novel insight into a dynamic IL-17A (show IL17A Antibodies)-CXCR2-neutrophil axis during acute segmented filamentous bacteria colonization and demonstrate a central role for neutrophils in limiting segmented filamentous bacteria expansion
Combining CSF1R (show CSF1R Antibodies) inhibitor with a CXCR2 antagonist blocked granulocyte infiltration of tumors and showed strong anti-tumor effects.
we conclude that CXCR2 is required for the recruitment of TANs, which in turn can suppress antitumor T-cell responses. We showed that CXCR2 ligands, particularly CXCL5 (show CXCL5 Antibodies), are elevated in both human and mouse PDA.
Results demonstrated that complete Freund's adjuvant increased CXCL1 (show CXCL1 Antibodies) and CXCR2 expression in the dorsal root ganglion, with the cellular distribution in all sizes neurons. In addition, specific inhibition of CXCR2 in the dorsal root ganglion attenuated established inflammatory pain.
postnatal development of the intestinal microbiota is an important susceptibility factor for experimental biliary atresia, which involves Cxcr2 signaling
this study demonstrates CXCR2-driven activation of NLRP3 (show NLRP3 Antibodies) inflammasome in macrophages, and indicates a potential host-directed therapeutic target to limit the damaging inflammation associated with overt production of proinflammatory IL-1beta (show IL1B Antibodies)
upregulation of CCRL2 (show CCRL2 Antibodies) observed under inflammatory conditions is functional to finely tune CXCR2-mediated neutrophil recruitment at sites of inflammation.
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified.
C-X-C chemokine receptor type 2
, interleukin 8 receptor beta
, interleukin-8 receptor CXCR2
, CXCR2 gene for IL8 receptor type B
, GRO/MGSA receptor
, IL-8 receptor type 2
, IL-8R B
, chemokine (CXC) receptor 2
, high affinity interleukin-8 receptor B
, interleukin 8 receptor B
, interleukin 8 receptor type 2
, interleukin 8 receptor, beta
, interleukin-8 receptor type B
, chemokine receptor CXCR2
, interleukin 8 receptor, alpha
, IL-8 receptor alpha chain
, chemokine (C-X-C) receptor 2
, IL-8 receptor
, High affinity interleukin-8 receptor B
, interleukin-8 receptor, beta