anti-RAN Binding Protein 2 Antibodies

Protein Summary

RAN is a small GTP-binding protein of the RAS superfamily that is associated with the nuclear membrane and is thought to control a variety of cellular functions through its interactions with other proteins. This gene encodes a very large RAN-binding protein that immunolocalizes to the nuclear pore complex. The protein is a giant scaffold and mosaic cyclophilin-related nucleoporin implicated in the Ran-GTPase cycle. The encoded protein directly interacts with the E2 enzyme UBC9 and strongly enhances SUMO1 transfer from UBC9 to the SUMO1 target SP100. These findings place sumoylation at the cytoplasmic filaments of the nuclear pore complex and suggest that, for some substrates, modification and nuclear import are linked events. This gene is partially duplicated in a gene cluster that lies in a hot spot for recombination on chromosome 2q.

Alternative names and synonyms associated with RAN Binding Protein 2 (RANBP2)

• RAN binding protein 2 (RANBP2) antibody
• RAN binding protein 2 (Ranbp2) antibody
• E3 SUMO-protein ligase RanBP2 (LOC474539) antibody
• RAN binding protein 2 (ranbp2) antibody
• E3 SUMO-protein ligase RanBP2 (LOC100511376) antibody

• A430087B05Rik antibody
• AI256741 antibody
• ane1 antibody
• IIAE3 antibody
• nup358 antibody
• Show all synonym aliases
• RANBP2 antibody
• RGD1560047 antibody
• trp1 antibody
• trp2 antibody

Protein level used designations for RANBP2

358 kDa nucleoporin , E3 SUMO-protein ligase RanBP2 , P270 , nuclear pore complex protein Nup358 , nucleoporin 358 , nucleoporin Nup358 , ran-binding protein 2 , transformation-related protein 2 , RAN binding protein 2 , p270 , e3 SUMO-protein ligase RanBP2-like