Protein Summary

The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.

Alternative names and synonyms associated with CNTNAP1

• contactin associated protein 1 (CNTNAP1) antibody
• contactin associated protein 1 (cntnap1) antibody
• contactin associated protein 1 (Cntnap1) antibody
• contactin associated protein-like 1 (Cntnap1) antibody

• AI841080 antibody
• Caspr antibody
• CNTNAP antibody
• CNTNAP1 antibody
• NCP1 antibody
• Show all synonym aliases
• Nrxn4 antibody
• p190 antibody
• shm antibody

Protein level used designations for CNTNAP1

contactin associated protein 1 , contactin-associated protein 1-like , caspr1 , contactin-associated protein 1 , neurexin 4 , neurexin IV , neurexin-4 , p190 , paranodin , MHDNIV , neurexin 4 (contactin associated protein)