Numb Homolog (Drosophila)-Like Proteins

4 Numb Homolog (Drosophila)-Like (NUMBL) Proteins from 3 manufacturers are available on www.antibodies-online.com.

Data Quality
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Type
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    Protein
Antigen
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Reactivity
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Application
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Host
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Binding Specificity
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Conjugate
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Protein Type
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Format
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4 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3131350
$9,371.15
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 60 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3094283
$9,371.15
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 60 Business Days
Recombinant Protein, HEK-293 Cells (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2727806
$932.80
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityRat (Rattus)
Application ELISA
Order details Cat. No. ABIN1475268
$3,773.00
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
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Numb Homolog (Drosophila)-Like (NUMBL) Protein Profile

Protein Summary

Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of embryonic neurogenesis. Also required postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. Negative regulator of NF-kappa-B signaling pathway. The inhibition of NF- kappa-B activation is mediated at least in part, by preventing MAP3K7IP2 to interact with polyubiquitin chains of TRAF6 and RIPK1 and by stimulating the 'Lys-48'-linked polyubiquitination and degradation of TRAF6 in cortical neurons.

Alternative names and synonyms associated with Numb Homolog (Drosophila)-Like (NUMBL)

  • NUMB like, endocytic adaptor protein (NUMBL) antibody
  • numb homolog-like L homeolog (numbl.L) antibody
  • NUMB-like, endocytic adaptor protein (Numbl) antibody
  • numb-like (Numbl) antibody
  • CAG3A antibody
  • CTG3a antibody
  • NBL antibody
  • numb antibody
  • NUMB-R antibody
  • NUMBLIKE antibody
  • NUMBR antibody
  • TNRC23 antibody

Protein level used designations for NUMBL

numb homolog-like , numb-like protein , numb-related protein

GENE ID SPECIES
100068203 Equus caballus
100462918 Xenopus laevis
9253 Homo sapiens
292732 Rattus norvegicus
612491 Canis lupus familiaris
510973 Bos taurus
18223 Mus musculus
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