Browse our anti-Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) Antibodies

Full name:: anti-Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) Antibodies (PVRL1)

On www.antibodies-online.com are 92 Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) Antibodies from 18 different suppliers available. Additionally we are shipping Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) Proteins (21) and Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) Kits (18) and many more products for this protein. A total of 145 Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) products are currently listed.

Synonyms:: AI835281, AW549174, cd111, cd112, clped1, ed4, higr, hveb, hvec, nectin-1, nectin-2, ofc7, prr, prr1, prr2, pvrl1, pvrl2, pvrl2.L, pvrr, pvrr1, pvrr2, sk-12

list all antibodies	Gene Name	GeneID	UniProt
	PVRL1	5818	Q15223
	PVRL1	58235	Q9JKF6
	PVRL1	192183
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Most Popular Reactivities for anti-Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) Antibodies

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Relevant Pathways for anti-Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) Antibodies

Cell-Cell Junction Organization

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More Antibodies against Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) Interaction Partners

Human Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) interaction partners

Pseudorabies virus infects host cells via both human and swine nectin-1.
In a transgenic mouse line with high expression of nectin-1Ig, significant protection from the infection with 30 and 300 MLD50 was observed .
nectin-1 is expressed in human hair follicles and there is a p63 (show RPE65 Antibodies)-responsive element in the NECTIN1 promoter
The viral entry receptor Nectin-1 is also internalized during HSV-1 infection in a Cbl (show CBL Antibodies)-dependent mechanism, and that increases the opportunity of the virus to spread to uninfected cells.
HSV gD is able to disrupt intercellular homophilic trans-interaction of nectin-1 and induce a rapid redistribution of nectin-1 from cell junctions.
PVRL1 variants make a contribution to non syndromic Cleft Lip with/without Cleft palate in Turkish patients.
PDZD11 forms a complex with nectin-1 and nectin-3 (show PVRL3 Antibodies), and its PDZ domain (show INADL Antibodies) interacts directly with the PDZ (show INADL Antibodies)-binding motif of nectin-1.
mutations in exons 2 and 5 of PVRL1, and T334A, A391T, G1183A in the alpha-spliced transcript, and G1082T in the beta-spliced transcript do not participate in the development of non-syndromic cleft of the lip and/or palate in patients from Guangdong.
data suggests that E-cadherin regulates assembly of nectin junctions through alpha-catenin-induced remodeling of the actin cytoskeleton around the cadherin clusters.
The results showed that the interface between the BV gD and nectin-1 molecule is not geometrically complementary.

Mouse (Murine) Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) interaction partners

Nectin-1 promotes chlamydial infection in the female genital tract but does not appear to contribute to rectal infection in male mice.
nectin-1 regulates the neuronal activities in the CA3 (show CA3 Antibodies) region of the hippocampus.
Novel type of cell adhesion apparatus is mediated by Nectin-1 and Nectin-4 (show PVRL4 Antibodies). It's implicated in prolactin receptor (show PRLR Antibodies) signaling for mammary gland development.
These results indicate that the nectin-1 spots regulate the branching of mitral cell dendrites in the deep sub-lamina of the EPL and suggest that the nectin-1 spots are required for odor information processing in the olfactory bulb.
Results indicate that the nectin-1 spots constitute a novel adhesion apparatus that tethers mitral cell dendrites in a dendritic meshwork structure of the developing mouse olfactory bulb
results demonstrate a role for both nectin-1 and HVEM (show TNFRSF14 Antibodies) as receptors and suggest a further receptor which appears much less efficient.
Pvrl1 is a bona fide target gene of the transcription factor p63 (show CKAP4 Antibodies), whereas Pvrl4 (show PVRL4 Antibodies) regulation is linked to epidermal differentiation and is under Irf6 (show IRF6 Antibodies)
In summary, herpes simplex virus 1 entry into epidermis was shown to strongly depend on the presence of nectin-1, but the restricted presence of HVEM (show TNFRSF14 Antibodies) can potentially replace nectin-1 as a receptor.
This study demonstrated that nectin1- and nectin3 (show PVRL3 Antibodies)-mediated interactions between Cajal-Retzius cells cells and migrating neurons are critical for radial migration
PRR1 nectin-1 plays a role in the formation of intimal thickening after carotid artery ligation.

Pig (Porcine) Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) interaction partners

Pseudorabies virus infects host cells via both human and swine nectin-1.
Contribution of the second and third Ig-like domains of nectin-1 was analysed by generating transgenic mice expressing the entire ectodomain of nectin-1 fused to the porcine Fc portion.
Results demonstrate that a soluble form of the first domain of porcine nectin-1 is able to exert a significant antiviral effect against pseudorabies virus infection.

Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) Antigen Profile

Antigen Summary

This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.

Alternative names and synonyms associated with Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1)

nectin cell adhesion molecule 1 (NECTIN1) antibody
nectin-1 (LOC100145553) antibody
Poliovirus receptor-related protein 1 (pvrl1) antibody
nectin cell adhesion molecule 1 (nectin1) antibody
nectin cell adhesion molecule 1 (Nectin1) antibody
poliovirus receptor-related 1 (herpesvirus entry mediator C) (PVRL1) antibody
nectin cell adhesion molecule 2 L homeolog (nectin2.L) antibody

AI835281 antibody
AW549174 antibody
cd111 antibody
cd112 antibody
clped1 antibody
ed4 antibody
higr antibody
hveb antibody
hvec antibody
nectin-1 antibody
nectin-2 antibody
ofc7 antibody
prr antibody
prr1 antibody
prr2 antibody
pvrl1 antibody
pvrl2 antibody
pvrl2.L antibody
pvrr antibody
pvrr1 antibody
pvrr2 antibody
sk-12 antibody

Protein level used designations for PVRL1

, , , , , , , , , , , , , , , , , , , , , ectodermal dysplasia 4 (Margarita Island type) herpes virus entry mediator C herpesvirus Ig-like receptor nectin 1 poliovirus receptor-like 1 poliovirus receptor-related protein 1 poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) poliovirus receptor-related 1 (herpesvirus entry mediator C) Poliovirus receptor-related protein 1 herpesvirus entry mediator C nectin-1 alpha nectin-1 delta nectin) poliovirus receptor-related 1 (herpesvirus entry mediator C nectin-1 poliovirus receptor-related 1 nectin poliovirus receptor related protein nectin 2 nectin cell adhesion molecule 2 L homeolog nectin-2alpha poliovirus receptor-related 2 (herpesvirus entry mediator B) L homeolog

GENE ID	SPECIES
5818	Homo sapiens
489363	Canis lupus familiaris
710072	Macaca mulatta
100074768	Ornithorhynchus anatinus
100145553	Xenopus (Silurana) tropicalis
100286721	Salmo salar
100564991	Anolis carolinensis
58235	Mus musculus
192183	Rattus norvegicus
397247	Sus scrofa
100341399	Oryctolagus cuniculus
533492	Bos taurus
100724766	Cavia porcellus
100857875	Gallus gallus
447468	Xenopus laevis

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