Browse our anti-Cyclin B2 (CCNB2) Antibodies

Human Cyclin B2 (CCNB2) interaction partners

1. nuclear division cycle 80, cyclin B2 and topoisomerase 2alpha may serve important roles in adrenocortical tumor development.

2. Data show that Islet-1 (ISL1) activated the expression of cyclin B1 (CCNB1), cyclin B2 (CCNB2) and c-myc (c-MYC) genes by binding to the conserved binding sites on their promoters or enhancers.

3. Data show that the cyclin B2 was overexpressed in bladder cancer tissue.

4. overexpression of CCNB2 protein is associated with clinical progression and poor prognosis in non-small cell lung cancer

5. Cyclin B1 and cyclin B2 are interchangeable for ability to promote G2 and M transition in HeLa cells.

6. there was no significance in the 5-year overall survival rates among the patients with squamous cell carcinoma between expressing lower and higher level of cyclin B2 mRNA

7. Suggest that cytoplasmic CCNB2 may function as an oncogene and could serve as a potential biomarker of unfavorable prognosis over short-term follow-up in breast cancer.

8. The radiosensitizing effect of paclitaxel on KB cells may be due to the down-regulated expression of PRC1 and cyclin B2.

9. The relative expression level of circulating CCNB2 mRNA in cancer patients was significantly higher than that in normal controls and benign diseases group. Circulating CCNB2 mRNA level significantly correlated with cancer stage and metastasis status.

10. Data suggest that cyclin A2 helps initiate mitosis, in part through its effects on cyclin B1, and that cyclins B1 and B2 are particularly critical for the maintenance of the mitotic state.

11. Overexpression of B-type cyclins alters chromosomal segregation

12. p300 binds to multiple NF-Y trimers to regulate cyclin B2 promoter function

13. cyclin B2 expression in colorectal adenocarcinoma is dependent on NF-Y

14. severe reduction by separate RNA interference of either cyclin B1 or cyclin B2 protein levels results in little or no alteration of the cell cycle and, more specifically, of mitosis progression

15. This gene may be used as a very reliable biomarker of lung adenocarcinoma.

16. The CCNA1, CCNB1, CCNB2, PRM1, and PRM2 messenger RNA transcript ratios were significantly decreased in patients with spermatogenic disorders. Transcript ratios in patients with successful sperm retrieval were higher than with failed sperm retrieval.

Mouse (Murine) Cyclin B2 (CCNB2) interaction partners

1. These results have revealed a hidden compensatory mechanism between Cyclin B1 and Cyclin B2 in regulating MPF and oocyte meiotic resumption.

2. Rate of translation of Cyclin B1 and B2 proteins, together with their degradation, is a major determinant of their divergent temporal accumulation during oocyte maturation. The Cdk1-independent translation of Ccnb2 mRNA strongly suggest that this Cyclin is present in prophase and may play a critical role in setting the stockpile of Cyclin B protein for the assembly of pre-maturation promoting factor.

3. Report roles for cyclin B2 and p53 in centrosome separation that may be perturbed in many human cancers.

4. Hec1-dependent cyclin B2 stabilization during early metaphase is important for early-stage spindle assembly.

5. Menin may inhibit MEN1 insulinoma by suppressing cyclin B2 expression via histone modification.

6. this study identifies a correlation between the presence of AIRE and proteasomal breakdown of cyclin B2, which leads us to speculate that cyclin B2 could be a target of AIRE's E3-ubiquitin ligase activity

7. menin-mediated repression of cyclin B2 is crucial for inhibiting G(2)/M transition and cell proliferation through a previously unrecognized molecular mechanism for menin-induced suppression of MEN1 tumorigenesis

Zebrafish Cyclin B2 (CCNB2) interaction partners

1. intestinal clock controls the expression of key cell cycle regulators, such as cdc2, wee1, p21, PCNA and cdk2, but only weakly influences cyclin B1, cyclin B2 and cyclin E1 expression.

Xenopus laevis Cyclin B2 (CCNB2) interaction partners

1. These results demonstrate that the proper localization of cyclin B2 is essential for bipolar spindle formation in Xenopus oocytes.

2. These results show that ElrA and AUF1 bind to cyclin B2 mRNA independent of cytoplasmic polyadenylation elements and function by binding other elements.