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Guinea Pig Polyclonal DP1 Primary Antibody for WB - ABIN610714
David, Solimena, De Camilli: Autoimmunity in stiff-Man syndrome with breast cancer is targeted to the C-terminal region of human amphiphysin, a protein similar to the yeast proteins, Rvs167 and Rvs161. in FEBS letters 1994
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COMMD9 participates in TFDP1/E2F1 (show E2F1 Antibodies) activation and plays a critical role in non-small cell lung cancer.
Here, the authors show that an acidic region of DP1 (show PTGDR Antibodies), whose function has remained elusive, binds to the plekstrin homology (PH) domain of the p62 (show GTF2H1 Antibodies) subunit of TFIIH (show GTF2H1 Antibodies) that contributes to transcriptional activation.
role for E2F1 (show E2F1 Antibodies) and TFDP1 in the transcriptional regulation of PITX1 (show PITX1 Antibodies) in articular chondrocytes
According to our study results, the gene TFDP1 and the cell cycle pathway are strongly associated with high-grade glioblastoma multiforme (GBM); this result may provide new insights into the pathogenesis of GBM.
Amplification of CUL4A (show CUL4A Antibodies), IRS2 (show IRS2 Antibodies), and TFDP1 genes showed a significant difference in disease-free survival by both univariate and multivariate survival analyses in intrahepatic cholangiocarcinoma.
The TFDP1 indel84 mutation generates a gain-of-function phenotype by increasing cell proliferation, migration, and invasion of colorectal cancer cells.
somatic mutations in DP-1 (show PTGDR Antibodies) uncouple normal control of the E2F (show E2F1 Antibodies) pathway, and thus define a new mechanism that could contribute to aberrant proliferation in tumor cells
The authors demonstrate that adenovirus E1A (show BCKDHA Antibodies) binds to E2F/DP (show E2F1 Antibodies)-1 (show PTGDR Antibodies) complexes through a direct interaction with DP-1 (show PTGDR Antibodies) and may selectively activate a subset of E2F (show E2F1 Antibodies)-regulated cellular genes during infection.
the DP-1 (show PTGDR Antibodies) "Stabilon" domain was a C-terminal acidic motif and was quite important for DP-1 (show PTGDR Antibodies) stability.
13q34 amplification may be of relevance in tumor progression of breast cancers by inducing overexpression of CUL4A (show CUL4A Antibodies) and TFDP1, important in cell cycle regulation. These genes were also overexpressed in non-basal-like tumor samples.
Kbtbd5 (show KBTBD5 Antibodies) regulates skeletal muscle myogenesis through the regulation of E2F1 (show E2F1 Antibodies)-DP1 (show REEP5 Antibodies) activity
Cell cycle suppression by Cdk5 (show CDK5 Antibodies) is made through the formation of a previously unknown complex consisting of the p35 (show CDK5R1 Antibodies)-Cdk5 (show CDK5 Antibodies) dimer and E2F1 (show E2F1 Antibodies), which excludes the E2F1 (show E2F1 Antibodies) cofactor, DP1 (show REEP5 Antibodies), thus inhibiting E2F1 (show E2F1 Antibodies) binding to the promoters of various cell cycle genes.
Persistent PP2A (show PPP2R2B Antibodies) expression prevented the appearance of the phosphorylated form of DP-1 required for cellular differentiation and reversal of dysplasia after loss of oncogene (show RAB1A Antibodies) expression.
Results show that Dp1 (show REEP5 Antibodies) is largely dispensable for embryonic development, despite the absolute extraembryonic requirement for Dp1 (show REEP5 Antibodies).
The authors propose that these dual functions of DP1 can promote and stabilize biphasic Wnt (show WNT2 Antibodies)-on and Wnt (show WNT2 Antibodies)-off states in response to a gradual gradient of Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signalling to determine differential cell fates.
This gene encodes a member of a family of transcription factors that heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. The encoded protein functions as part of this complex to control the transcriptional activity of numerous genes involved in cell cycle progression from G1 to S phase. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1, 15, and X.
RNA-binding protein MEX3A
, transcription factor Dp-1, like
, DRTF1-polypeptide 1
, E2F dimerization partner 1
, E2F-related transcription factor
, cell cycle regulatory transcription factor DP1
, transcription factor Dp-1
, transcription factor Dp-1 a
, transcription factor Dp-1-like