Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.
Alternative names and synonyms associated with HDAC8
histone deacetylase 8 (CC1G_05302) ELISA Kit
histone deacetylase 8 (hdac8) ELISA Kit
histone deacetylase 8 (HDAC8) ELISA Kit
histone deacetylase 8 (Hdac8) ELISA Kit
histone deacetylase 8 L homeolog (hdac8.L) ELISA Kit