Browse our anti-Arginase, Liver (ARG1) Antibodies

Human Arginase, Liver (ARG1) interaction partners

1. ARG1 gene polymorphisms and their association in individuals with essential hypertension in Pakistan has been presented.

2. A subset of well-differentiated hepatocellular carcinomas are arginase-1 negative.

3. The data in this study suggest that arginase I inhibition potentially represents a novel therapeutic target for the prevention and/or treatment of bronchopulmonary dysplasia-associated pulmonary hypertension.

4. this study shows that infiltrating macrophages expressing Arg1 are present in active allergic contact dermatitis lesions

5. High arginase expression is associated with glioblastoma.

6. Report the value of Arg-1 in distinguishing HepPar-1-positive prostatic carcinoma from hepatocellular carcinoma at metastatic sites or cases of liver metastasis from prostate carcinoma.

7. AEG-1 (show MTDH Antibodies) is positively activated in the tumorigenesis and deterioration of NSCLC.

8. Arginase-1 expression is common (62.5%) in hepatoid adenocarcinoma and hence it is not useful in distinguishing hepatocellular carcinoma from hepatoid adenocarcinoma.

9. Arginase 1 was highly expressed by tumor-associated Gr1+ microglia and macrophages.

10. The authors report here that Candida albicans blocks nitric oxide production in human-monocyte-derived macrophages by induction of host arginase activity.

Cow (Bovine) Arginase, Liver (ARG1) interaction partners

1. Activity of arginase before and at the time of parturition might be a potential marker for occurrence of metritis, especially in cows that develop retained fetal membranes.

2. Arginase has a role in preventing angiogenesis in endothelial cells exposed to hypoxia

3. Ang II (show AGT Antibodies) increases endothelial arginase activity/expression through a p38 MAPK (show MAPK14 Antibodies)/ATF-2 (show ATF2 Antibodies) pathway leading to reduced endothelial NO production

4. results indicate that arginase induction depends in part on epidermal growth factor (EGF (show EGF Antibodies)) receptor (show EGFR Antibodies) activity, and that EGFR (show EGFR Antibodies) inhibitors may attenuate vascular remodeling without affecting nitric oxide release

5. high glucose (HG)-treated bovine coronary endothelial cells (BCECs) showed increased arginase activity and diminished NO production

Mouse (Murine) Arginase, Liver (ARG1) interaction partners

1. This study shows for the first time that diabetes-induced increases in arginase 1 expression promotes endothelial cell senescence through the activation of p16INK4A and p53 (show TP53 Antibodies) signaling pathways.

2. findings identified a novel function of the VEGFR1 (show FLT1 Antibodies) signaling in avoiding over-expression of Arginase 1 potentially to maintain the proper innate immune response.

3. Up-regulation of arginase 1 expression/activity in vascular endothelial cells has an integral role in diet-induced cardiovascular dysfunction and metabolic syndrome.

4. Complete ablation of Arg1 in the lung affects mRNA abundance of arginine-transporting and -metabolizing genes, and pro-inflammatory genes, but not methacholine responsiveness or accumulation of inflammatory cells.

5. Data suggest that Arg1 mRNA and protein expression in liver are significantly higher in obese mice (fed high-fat diet) than in control mice; hepatic Arg1 levels positively correlate with plasma Arg1 levels and negatively correlate with L-arginine (show GATM Antibodies) bioavailability in plasma. Increased expression of hepatic Arg1 and reduced plasma L-arginine (show GATM Antibodies) and NO(2)(-) may lead to vascular endothelial dysfunction even in early obesity.

6. Data suggest that chronic hypoxia enhances HIF-2alpha stability, which causes increased arginase expression and dysregulates normal vascular NO homeostasis.

7. Deletion of Arg1 in hematopoietic cells adversely affects blood leukocyte counts and increases foam cell formation. However, no effects on atherosclerosis could be demonstrated, indicating that hematopoietic Arg1 function is not a decisive factor in atherosclerotic plaque formation.

8. diabetes-dependent increase in renal arginase-2 (show ARG2 Antibodies) expression also requires arginase-1 expression in macrophages

9. this study shows that mice lacking Arg1 in macrophages develop increased allergic contact hypersensitivity

10. this study shows that Ron (show MST1R Antibodies) is expressed in a subpopulation of macrophages during chronic inflammation induced by obesity that exhibit a repair phenotype as determined by the expression of arginase 1

Pig (Porcine) Arginase, Liver (ARG1) interaction partners

1. The immunosuppressive effect of a purified substance (ISF (show ATP6V0A2 Antibodies)) in the culture medium of neonatal pig liver fragments was due to arginase activity that decreased arginine concentration in culture medium, not to another function of ISF (show ATP6V0A2 Antibodies).

2. Results show that ischemia markedly potentiated the expression of arginase-1, and also induced the SOD2 (show SOD2 Antibodies) in the wound tissue.