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findings show that at least 4 IFN-gamma (show IFNG Proteins)-inducible Gbps--Gbp1 (show GBP1 Proteins), Gbp6, Gbp7 (show GBP7 Proteins), and Gbp10--conferred cell-autonomous immunity to listerial or mycobacterial infection within macrophages and gene-deficient animals
Guanylate-binding proteins, such as GBP6, are induced by interferon and hydrolyze GTP to both GDP and GMP (Olszewski et al., 2006
macrophage activation 2 like
, GTP-binding protein 6
, guanine nucleotide-binding protein 6
, guanylate-binding protein 6