Browse our phospholipid Scramblase 1 Proteins (PLSCR1)

Full name:: phospholipid Scramblase 1 Proteins (PLSCR1)

On www.antibodies-online.com are 9 phospholipid Scramblase 1 (PLSCR1) Proteins from 4 different suppliers available. Additionally we are shipping phospholipid Scramblase 1 Antibodies (51) and phospholipid Scramblase 1 Kits (35) and many more products for this protein. A total of 106 phospholipid Scramblase 1 products are currently listed.

Synonyms:: MGC84969, MGC148322, MmTRA1a, MmTRA1b, Nor1, PLSCR1, PLSCR2, Tra1, Tra1a, Tra1b, Tras1, Tras2

list all proteins	Gene Name	GeneID	UniProt
Rat PLSCR1	PLSCR1	117540	P58195
	PLSCR1	5359	O15162
	PLSCR1	22038	Q9JJ00
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phospholipid Scramblase 1 Proteins (PLSCR1) by Origin

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Relevant Pathways for phospholipid Scramblase 1 Proteins

Cellular Response to Molecule of Bacterial Origin

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More Proteins for phospholipid Scramblase 1 Interaction Partners

Human phospholipid Scramblase 1 (PLSCR1) interaction partners

Inhibition of PLSCR1 decreased the antiviral activity of IFN against HBV.
Data suggest that PLSCR1 is involved in viral entry; here, herpes simplex viruses activate PLSCR1 and up-regulate flipping of phosphatidylserines and AKT (show AKT1 Proteins) to outside of plasma membrane shortly following HSV-1 or HSV-2 exposure. (PLSCR1 = phospholipid scramblase 1; AKT (show AKT1 Proteins) = proto-oncogene c-Akt (show AKT1 Proteins))
wogonoside promotes the expression of PLSCR1 and enhances its nuclear translocation and binding to the 1, 4, 5-trisphosphate receptor 1 (IP3R1 (show ITPR1 Proteins)) promoter in AML (show RUNX1 Proteins) patient-derived primary cells. Wogonoside activates IP3R1 (show ITPR1 Proteins), in turn, promotes release of Ca(2 (show CA2 Proteins)+) from endoplasmic reticulum, and eventually leads to cell differentiation.
Data indicate heterogeneous expression of phospholipid scramblase 1 (PLSCR1) and suggest its possible implication in the response to anticancer therapies, especially to drugs promoting protective autophagy.
Human phospholipid scramblase 1 has five histidine residues and point mutations of histidine residues to alanine in hPLSCR1 resulted in 60 % loss in nuclease (show DCLRE1C Proteins) activity.
directed mutagenesis revealed the importance of c-Myc (show MYC Proteins) binding sites from -751 to -756 and -548 to -553 on the promoter of hPLSCR1in transcriptionally regulating the expression of hPLSCR1.
PLSCR1 positively regulates hepatic carcinoma cell proliferation and migration through interacting with midkine (show MDK Proteins)
Suggest role for PLSCR1 in negatively regulating trophoblast fusion rather than directly promoting fusion.
PLSCR1 mediates the antiviral activity and anticarcinogenesis against hepatitis B virus by regulating HBx stability.
affinity of SCR for cholesterol-rich domains in membranes

Mouse (Murine) phospholipid Scramblase 1 (PLSCR1) interaction partners

PLSCR1 aggravates anaphylactic reactions by increasing Fc epsion RI-dependent mast cell degranulation.
Genetic knockdown of PLSCR1 activity reduces intracellular calcium dysregulation, prevents phosphatidylserine externalization, and enables months-long protection of vector-transduced, transgene-expressing cells from microglial phagocytosis.
Phospholipid scramblase 1 regulates phosphatidylserine exposure in response to oxygen stress, leading to beta2-glycoprotein I and IgM binding and lipid-mediated, inflammatory responses.
Lipopolysaccharide treatment resulted in increased expression of phospholipid scramblase 1(PLSCR-1) and decrease in phospholipid scramblase 4(Plscr4 (show PLSCR4 Proteins) )messenger RNA demonstrating modulation of PLSCR-1 and PLSCR-4 (show PLSCR4 Proteins) in lipopolysaccharide-induced preterm birth
Study demonstrates that PLSCR1 is a TLR9 (show TLR9 Proteins)-interacting protein that plays an important role in pDC's type 1 IFN responses by regulating TLR9 (show TLR9 Proteins) trafficking to the endosomal compartment.
the capacity of PLSCR1 to augment G-CSF (show CSF3 Proteins)-dependent production of mature neutrophils from myeloid progenitors is unrelated to its reported activities at the endofacial surface of the plasma membrane but does require entry of the protein into the nucleus
PLSCR1 appears to influence progression of UV-induced apoptosis and could be a point of regulation or intervention during programmed cell death
PLSCR1, which is itself an IFN-stimulated gene-encoded protein, provides a mechanism for amplifying and enhancing the IFN response through increased expression of a select subset of potent antiviral genes
PLSCR1 binds to the promoter region of the IP3R1 (show ITPR1 Proteins) gene to enhance its expression
These findings demonstrate a functional interdependence between onzin and PLSCR1.

phospholipid Scramblase 1 (PLSCR1) Protein Profile

Protein Summary

may act as a downstream mediator of immune response in IgE receptor signaling\; may transport phospholipids in the plasma membrane

Alternative names and synonyms associated with phospholipid Scramblase 1 (PLSCR1)

phospholipid scramblase 1 L homeolog (plscr1.L)
phospholipid scramblase 1 (PLS1)
phospholipid scramblase 1 (PVX_111580)
phospholipid scramblase 1 (PLSCR1)
phospholipid scramblase 1 (plscr1)
phospholipid scramblase 1 (Plscr1)
phospholipid scramblase 1 (LOC100712949)
phospholipid scramblase 1 (PLSCR2)
phospholipid scramblase 1 (LOC100341366)
phospholipid scramblase 1 (LOC611500)

MGC84969 protein
MGC148322 protein
MmTRA1a protein
MmTRA1b protein
Nor1 protein
PLSCR1 protein
PLSCR2 protein
Tra1 protein
Tra1a protein
Tra1b protein
Tras1 protein
Tras2 protein

Protein level used designations for PLSCR1

phospholipid scramblase 1 , PL scramblase 1 , ca(2+)-dependent phospholipid scramblase 1 , phospholipid scramblase 2 , erythrocyte phospholipid scramblase , transplantability-associated protein 1 , PL scramblase 2 , ca(2+)-dependent phospholipid scramblase 2

GENE ID	SPECIES
734475	Xenopus laevis
4839590	Scheffersomyces stipitis CBS 6054
5471430	Plasmodium vivax Sal-1
100125943	Bos taurus
100216165	Xenopus (Silurana) tropicalis
117540	Rattus norvegicus
5359	Homo sapiens
22038	Mus musculus
100712949	Cavia porcellus
100620055	Sus scrofa
513193	Bos taurus
100341366	Oryctolagus cuniculus
611500	Canis lupus familiaris
424883	Gallus gallus

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