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Browse our phospholipid Scramblase 3 Proteins (PLSCR3)

Full name:: phospholipid Scramblase 3 Proteins (PLSCR3)

On www.antibodies-online.com are 11 phospholipid Scramblase 3 (PLSCR3) Proteins from 6 different suppliers available. Additionally we are shipping phospholipid Scramblase 3 Antibodies (51) and and many more products for this protein. A total of 71 phospholipid Scramblase 3 products are currently listed.

Synonyms:: 2210403O21Rik, 2610037N06Rik, ESTM3, Pls3, X83310, zgc:77051

list all proteins	Gene Name	GeneID	UniProt
	PLSCR3	57048	Q9NRY6
	PLSCR3	70310	Q9JIZ9
Rat PLSCR3	PLSCR3	360549	Q6QBQ4
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Human phospholipid Scramblase 3 (PLSCR3) interaction partners

The results revealed that Ca2+ and Mg2+ bind to Human phospholipid scramblase 3 (hPLSCR3) and trigger conformational changes mediated by aggregation.
Secreted Scr3 was taken up by HeLa cells, suggesting that Scr3 functions as a cell-to-cell transferable modulator carried by exosomes in a paracrine manner.
PLS3 is a downstream effector of PKC-delta in the mitochondria.
PLS3 as a critical regulator of mitochondrial structure and respiration, and CL transport in apoptosis.
This enzyme is a novel regulator of cardiolipin de novo biosynthesis and its resynthesis.
These findings indicate that phosphorylation of PLS3 by PKC-delta induces PLS3 activation to facilitate mitochondrial targeting of tBid and apoptosis.
Identification of Alix-type and Non-Alix-type ALG-2-binding sites in human phospholipid scramblase 3: differential binding to an alternatively spliced isoform and amino acid-substituted mutants
TRAIL-induced activation of PKC-delta mediates regulation of the phospholipid scramblase3-induced changes in cardiolipin.
Results show that binding affinities of the peptides are in the order hPLSCR1>hPLSCR3>hPLSCR2>hPLSCR4 for Ca2+ and in the order hPLSCR1>hPLSCR2>hPLSCR3>hPLSCR4 for Mg2+.

Mouse (Murine) phospholipid Scramblase 3 (PLSCR3) interaction partners

results suggest that Scr3 functions as a negative regulator of adipogenesis in 3T3-L1 cells at a specific differentiation stage and that decrease in the intracellular amount of Scr3 protein caused by reduction in Scr3 mRNA expression
expression of PLSCR3 may be required for normal adipocyte and/or macrophage maturation or function
identified previously unrecognized lipid metabolites that suggest a novel molecular link between obesity, inflammation and the downstream consequences associated with PLSCR3-deficiency

phospholipid Scramblase 3 (PLSCR3) Protein Profile

Protein Summary

May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system (By similarity).

Alternative names and synonyms associated with phospholipid Scramblase 3 (PLSCR3)

phospholipid scramblase 3 (PLSCR3)
phospholipid scramblase 3 (Plscr3)
phospholipid scramblase 3b (plscr3b)

2210403O21Rik protein
2610037N06Rik protein
ESTM3 protein
Pls3 protein
X83310 protein
zgc:77051 protein

Protein level used designations for PLSCR3

PL scramblase 3 , ca(2+)-dependent phospholipid scramblase 3 , Ca 2+ dependent phospholipid scramblase 3 , LOW QUALITY PROTEIN: phospholipid scramblase 3 , phospholipid scramblase 3 , phospholipid scramblase 1

GENE ID	SPECIES
57048	Homo sapiens
70310	Mus musculus
360549	Rattus norvegicus
510355	Bos taurus
100358458	Oryctolagus cuniculus
100072978	Equus caballus
489471	Canis lupus familiaris
100735353	Cavia porcellus
405802	Danio rerio

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