PLSCR3 Protein (AA 1-265) (His tag)
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- Target See all PLSCR3 Proteins
- PLSCR3 (phospholipid Scramblase 3 (PLSCR3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-265
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PLSCR3 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMAGYLPP KGYAPSPPPP YPVTPGYPEP ALHPGPGQAP VPAQVPAPAP GFALFPSPGP VALGSAAPFL PLPGVPSGLE FLVQIDQILI HQKAERVETF LGWETCNRYE LRSGAGQPLG QAAEESNCCA RLCCGARRPL RVRLADPGDR EVLRLLRPLH CGCSCCPCGL QEMEVQAPPG TTIGHVLQTW HPFLPKFSIQ DADRQTVLRV VGPCWTCGCG TDTNFEVKTR DESRSVGRIS KQWGGLVREA LTDADDFGLQ FPLDLDVR
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product PLSCR3 Protein
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phospholipid Scramblase 3 (PLSCR3) (AA 1-295) protein (GST tag)
PLSCR3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
phospholipid Scramblase 3 (PLSCR3) (AA 74-165) protein (GST tag)PLSCR3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
phospholipid Scramblase 3 (PLSCR3) (AA 1-265) protein (His tag)Crystallography grade PLSCR3 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
phospholipid Scramblase 3 (PLSCR3) (AA 1-266) protein (His tag)Crystallography grade PLSCR3 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
phospholipid Scramblase 3 (PLSCR3) (AA 1-295) protein (Strep Tag)Crystallography grade PLSCR3 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
phospholipid Scramblase 3 (PLSCR3) (AA 1-296) protein (Strep Tag)Crystallography grade PLSCR3 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
phospholipid Scramblase 3 (PLSCR3) protein (Myc-DYKDDDDK Tag)PLSCR3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol 0.4M urea
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- PLSCR3 (phospholipid Scramblase 3 (PLSCR3))
- Alternative Name
- PLSCR3 (PLSCR3 Products)
- Synonyms
- 2210403O21Rik Protein, 2610037N06Rik Protein, ESTM3 Protein, X83310 Protein, Pls3 Protein, zgc:77051 Protein, phospholipid scramblase 3 Protein, phospholipid scramblase 3b Protein, PLSCR3 Protein, Plscr3 Protein, plscr3b Protein
- Background
- PLSCR3 may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. This protein may play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. It seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages. Recombinant human PLSCR3 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 30.9 kDa (288aa)
- NCBI Accession
- NP_001188505
- UniProt
- Q9NRY6
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis
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