Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Human BRD4 Antibodies:
anti-Mouse (Murine) BRD4 Antibodies:
anti-Rat (Rattus) BRD4 Antibodies:
Go to our pre-filtered search.
Human Polyclonal BRD4 Primary Antibody for ICC, IF - ABIN438710
Rahman, Sowa, Ottinger, Smith, Shi, Harper, Howley: The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3. in Molecular and cellular biology 2011
Show all 3 Pubmed References
Human Polyclonal BRD4 Primary Antibody for ICC, IF - ABIN4285227
Zuber, Shi, Wang, Rappaport, Herrmann, Sison, Magoon, Qi, Blatt, Wunderlich, Taylor, Johns, Chicas, Mulloy, Kogan, Brown, Valent, Bradner, Lowe, Vakoc: RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia. in Nature 2011
Show all 2 Pubmed References
Human Polyclonal BRD4 Primary Antibody for ChIP, WB - ABIN2668492
Flajollet, Rachez, Ploton, Schulz, Gallais, Métivier, Pawlak, Leray, Issulahi, Héliot, Staels, Salbert, Lefebvre: The elongation complex components BRD4 and MLLT3/AF9 are transcriptional coactivators of nuclear retinoid receptors. in PLoS ONE 2013
Show all 2 Pubmed References
Brd4 associates with mitotic chromosomes throughout early zebrafish embryogenesis
The Brd4 acetyllysine-binding protein of RelA (show NFkBP65 Antibodies) is involved in activation of polyomavirus JC.
BRD4 phosphorylation regulates HPV E2-mediated viral transcription and cellular MMP-9 (show MMP9 Antibodies) expression
conclude that BRD3 (show BRD3 Antibodies)/4 and the FLT3 (show FLT3 Antibodies)-TAK1 (show MAP3K7 Antibodies)/NF-kB pathways collectively control a set of targets that are critically important for the survival of human MLL (show MLL Antibodies)-AF9 (show MLLT3 Antibodies) cells
Diverse gastric cancer cell lines of Asian and Brazilian origins differ in BRD4 and c-MYC (show MYC Antibodies) expression levels and sensitivity to BET inhibitors.
Together, dual inhibition of BRD4 and PI3K (show PIK3CA Antibodies) by SF2523 suppresses human prostate cancer cell growth in vitro and in vivo.
peroxisome proliferator activated receptor alpha peroxisome proliferator-activated receptor alpha (show PPARA Antibodies) PPAR-alpha (show PPARA Antibodies) nuclear receptor subfamily 1 group C member 1 (show PPARA Antibodies) peroxisome proliferative activated receptor alpha (show PPARA Antibodies) peroxisome proliferator-activated nuclear receptor alpha variant 3 (show PPARA Antibodies)
Brd4 is involved in different steps of the papillomavirus life cycle. (Review)
BRD4 and MYC (show MYC Antibodies) are essential for the expression of a subgroup of genes induced by class-I HDAC (show HDAC3 Antibodies) inhibitors.
Data show that BRD4 controls RUNX2 (show RUNX2 Antibodies) by binding to the enhancers (ENHs) and each RUNX2 (show RUNX2 Antibodies) ENH (show PDLIM5 Antibodies) is potentially controlled by a distinct set of TFs and c-JUN (show JUN Antibodies) as the principal pivot of this regulatory platform.
any of the molecules or processes in the network could be targeted to curb the oncogenic effects of c-Myc (show MYC Antibodies), just as BRD4 can be targeted. And since the targeting of metabolic enzymes has proved effective in mouse tumor models, it might be possible to develop new therapies based on the fact that c-Myc (show MYC Antibodies) has a role in controlling cellular metabolism
Using compound selectivity engineering and CRISPR/Cas9 genome editing, distinct functions for Erk5 (show MAPK7 Antibodies) and Brd4 in pluripotency regulation of mouse embryonic stem cells have been revealed.
Long-term treatment with bromodomain-containing protein 4 (BRD4) inhibitors caused telomere shortening in both mouse and human cells, suggesting BRD4 plays a role in telomere maintenance in vivo.
Fmr1 (show FMR1 Antibodies) knockout (KO) mice show widespread changes in histone marks as well as transcriptional misregulation resulting in increased expression of many critical synaptic genes. Data suggest that one chromatin target of FMRP (show FMR1 Antibodies), the reader protein Brd4, appears to be significantly involved in this transcriptional disruption.
The functional domains of mouse BRD4 and its role in transcription are described. Review.
Brd2 (show BRD2 Antibodies) and Brd4 genetic transcription required for Th17 cell development and adaptive immunity.
These data provide a detailed mechanism for how activated NF-kappaB (show NFKB1 Antibodies) and BRD4 control epithelial-mesenchymal transition initiation and transcriptional elongation in model airway epithelial cells in vitro and in a murine pulmonary fibrosis model in vivo.
DOT1L (show DOT1L Antibodies), via dimethylated histone H3 (show HIST3H3 Antibodies) K79, facilitates histone H4 (show HIST1H4H Antibodies) acetylation, which in turn regulates the binding of BRD4 to chromatin in acute lymphoblastic leukemia.
Acute induction of genes related to lipid accumulation in the livers of mice force-fed with fructose is associated with the induction of histone acetylation and BRD4 binding around these genes
Both mouse and human BRD4 have intrinsic histone acetyltransferase (show HAT Antibodies) activity.
the interaction between BRD4 and Mediator has functional importance for gene-specific transcriptional activation and for acute myeloid leukemia (show BCL11A Antibodies) maintenance.
The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15\;19)(q13\;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.
Bromodomain-containing protein 4B
, bromodomain-containing protein 4B
, bromodomain containing 4
, bromodomain-containing protein 4
, bromodomain 4
, bromodomain-containing protein 4-like
, bromodomain containing protein 4
, bromodomain-containing 4
, chromosome-associated protein
, bromodomain-containing 5
, fsh-like protein
, mitotic chromosome-associated protein