BRD4 antibody (AA 1313-1342)

Catalog No. ABIN3030205

Product Details anti-BRD4 Antibody

Target: BRD4 (Bromodomain Containing 4 (BRD4))

Binding Specificity: AA 1313-1342

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRD4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity (Details): Expected species reactivity: Mouse

Purification: Purified

Immunogen: A portion of amino acids 1313-1342 from the human protein was used as the immunogen for this BRD4 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the BRD4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the BRD4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for BRD4

Target: BRD4 (Bromodomain Containing 4 (BRD4))

Alternative Name: BRD4 (BRD4 Products)

Synonyms: brd4-b antibody, BRD4 antibody, fb18g03 antibody, wu:fb18g03 antibody, CAP antibody, HUNK1 antibody, HUNKI antibody, MCAP antibody, Brd5 antibody, WI-11513 antibody, bromodomain containing 4 L homeolog antibody, bromodomain containing 4 antibody, bromodomain-containing protein 4 antibody, brd4.L antibody, BRD4 antibody, brd4 antibody, LOC100409351 antibody, Brd4 antibody

Background: BRD4 is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. The gene has been implicated as the chromosome 19 target of translocation t(15,19)(q13,p13.1), which defines an upper respiratory tract carcinoma in young people.

UniProt: O60885

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interactome