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anti-Rat (Rattus) MYB Antibodies:
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Human Monoclonal MYB Primary Antibody for WB - ABIN1944794
Majello, Kenyon, Dalla-Favera: Human c-myb protooncogene: nucleotide sequence of cDNA and organization of the genomic locus. in Proceedings of the National Academy of Sciences of the United States of America 1987
Show all 3 Pubmed References
Cow (Bovine) Polyclonal MYB Primary Antibody for ELISA, WB - ABIN4285666
Fahl, Crittenden, Allman, Bender: c-Myb is required for pro-B cell differentiation. in Journal of immunology (Baltimore, Md. : 1950) 2009
Human Polyclonal MYB Primary Antibody for IHC (p), IHC - ABIN253301
Clappier, Cuccuini, Kalota, Crinquette, Cayuela, Dik, Langerak, Montpellier, Nadel, Walrafen, Delattre, Aurias, Leblanc, Dombret, Gewirtz, Baruchel, Sigaux, Soulier: The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL), the translocation defining a new T-ALL subtype in very young children. in Blood 2007
The analysis points to a critical role for Hoxa9 (show HOXA9 Antibodies) and PU.1 in distal regulation of c-myb expression in murine myeloid cells during iL-6 (show IL6 Antibodies)-induced cell differentiation.
Data suggest that the upregulations of Myb and Peg3 (show PEG3 Antibodies) are likely the key anti-cancer events of EGCG in vivo.
deficiency alters the expression of a crucial subset of TAL1 (show TAL1 Antibodies)- and NOTCH1 (show NOTCH1 Antibodies)-regulated genes, including the MYB and MYC (show MYC Antibodies) oncogenes, respectively.
MYB acts on MAPK (show MAPK1 Antibodies) signaling by directly regulating transcription of the gene encoding the negative modulator SPRY2 (show SPRY2 Antibodies).
This work provides important mechanistic insight into how spatiotemporal expression of the Rag genes is tightly controlled during B lymphocyte (show AKAP17A Antibodies) development to prevent mistimed dsDNA breaks and their deleterious consequences.
These results Myb as a critical component of the gene regulatory network controlling effector Treg cell differentiation and function.
Myb expands the ISC pool within which CRC (show SCRIB Antibodies) is initiated while co-operating with TSG (show TWSG1 Antibodies) loss
c-Myb regulates proliferation/differentiation of adventitial Sca1 (show ATXN1 Antibodies)+ vascular smooth muscle progenitor cells by transcriptional activation of myocardin (show MYOCD Antibodies).
the key role of the transcription factor c-Myb in regulating the T-bet-mediated anti-viral program, is reported.
p38 (show CRK Antibodies) and NOX1 (show NOX1 Antibodies) are essential for the protective effect of c-Myb and that NOX1 (show NOX1 Antibodies) acts upstream of p38 (show CRK Antibodies) activation.
Expression of the MYB-NFIB (show NFIB Antibodies) fusion oncogene (show RAB1A Antibodies) in mammary tissue resulted in hyperplastic glands that developed into adenocarcinoma.
A trend toward superior PFS was noted with the MYB/NFIB (show NFIB Antibodies) rearrangement, although this was not statistically significant. NGS revealed three tumors with 4q12 amplification, producing increased copies of axitinib-targeted genes PDGFR (show PDGFRB Antibodies)/KDR (show KDR Antibodies)/KIT.
Rearrangement of MYB did not affect OS.
Exosomes isolated from cultured AML (show RUNX1 Antibodies) or the plasma from mice bearing AML (show RUNX1 Antibodies) xenografts exhibited enrichment of miR (show MLXIP Antibodies)-150 and miR (show MLXIP Antibodies)-155. HSPCs cocultured with either of these exosomes exhibited impaired clonogenicity, through the miR (show MLXIP Antibodies)-150- and miR (show MLXIP Antibodies)-155-mediated suppression of the translation of transcripts encoding c-MYB
identification of SNPs within the IQCJ, NXPH1 (show NXPH1 Antibodies), PHF17 (show PHF17 Antibodies) and MYB genes partly explaining the large interindividual variability observed in plasma triglyceride levels in response to an n-3 fatty acid supplementation
The data indicate that MAZ (show MAZ Antibodies) is essential to bypass MYB promoter repression by RB family members and to induce MYB expression.
A mutant of c-Myb, D152V, specifically affects c-Myb's ability to regulate genes involved in differentiation, causing failure in c-Myb's ability to block differentiation.
l genetic alterations were limited to two fusion genes, EWSR1 (show EWSR1 Antibodies)-PATZ1 (show ZNF278 Antibodies) and SLMAP (show SLMAP Antibodies)-NTRK2 (show NTRK2 Antibodies), both in gangliogliomas. Alterations in BRAF (show BRAF Antibodies), FGFR1 (show FGFR1 Antibodies), or MYB account for most pathogenic alterations in low-grade neuroepithelial tumors
This gene encodes a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants.
, Avian myeloblastosis viral (v-myb) oncogene homolog
, v-myb myeloblastosis viral oncogene homolog (avian)
, transcriptional activator Myb-like
, gag-myb protein
, myb proto-oncogene protein
, myeloblastosis proto-oncogene product
, proto-oncogene c-Myb
, transcriptional activator Myb
, tumor-specific myb protein
, c-myb protein (140 AA)
, DNA-binding transcriptional regulator
, c-myb proto-oncogene