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MYB Products

(V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Categories

This gene encodes a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009].

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Featured MYB Categories

MYB Antibodies

High quality antibodies with extensive validation data.

MYB ELISA Kits

Reliable ELISA kits for a wide range of species.

MYB Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MYB Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (4)
Cat. No. ABIN190759
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6263449
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF, ICC
Validations
  • (1)
  • (2)
Cat. No. ABIN6263448
Quantity 100 μL
Datasheet Datasheet

Recommended MYB ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971104
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380230
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative DNA-Binding ELISA
Validations
Cat. No. ABIN5648636
Quantity 96 tests
Datasheet Datasheet

Recommended MYB Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311699
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311697
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3084207
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our MYB products

Huang, Zhang, Hou, Wang, Liu, Zhang, Chen, Zhu: "LncRNA AK023391 promotes tumorigenesis and invasion of gastric cancer through activation of the PI3K/Akt signaling pathway." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 194, (2018) (PubMed).

Srivastava, Bhardwaj, Arora, Singh, Azim, Tyagi, Carter, Wang, Singh: "MYB is a novel regulator of pancreatic tumour growth and metastasis." in: British journal of cancer, Vol. 113, Issue 12, pp. 1694-703, (2015) (PubMed).

Volpe, Clarke, Garcìa, Walton, Vegiopoulos, Del Pozzo, ONeill, Frampton, Dumon: "Regulation of the Flt3 Gene in Haematopoietic Stem and Early Progenitor Cells." in: PLoS ONE, Vol. 10, Issue 9, pp. e0138257, (2015) (PubMed).

Srivastava, Bhardwaj, Singh, Arora, McClellan, Grizzle, Reed, Singh: "Myb overexpression overrides androgen depletion-induced cell cycle arrest and apoptosis in prostate cancer cells, and confers aggressive malignant traits: potential role in castration resistance." in: Carcinogenesis, Vol. 33, Issue 6, pp. 1149-57, (2012) (PubMed).

Deisenroth, Thorner, Enomoto, Perou, Zhang: "Mitochondrial Hep27 is a c-Myb target gene that inhibits Mdm2 and stabilizes p53." in: Molecular and cellular biology, Vol. 30, Issue 16, pp. 3981-93, (2010) (PubMed).

Fahl, Crittenden, Allman, Bender: "c-Myb is required for pro-B cell differentiation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 9, pp. 5582-92, (2009) (PubMed).

Chen, Xu, Zeng, Li, Yin, Chen, Shao, Jin: "c-myb activates CXCL12 transcription in T47D and MCF7 breast cancer cells." in: Acta biochimica et biophysica Sinica, Vol. 42, Issue 1, pp. 1-7, (2009) (PubMed).

Clappier, Cuccuini, Kalota, Crinquette, Cayuela, Dik, Langerak, Montpellier, Nadel, Walrafen, Delattre, Aurias, Leblanc, Dombret, Gewirtz, Baruchel, Sigaux, Soulier: "The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL), the translocation defining a new T-ALL subtype in very young children." in: Blood, Vol. 110, Issue 4, pp. 1251-61, (2007) (PubMed).

Sramko, Markus, Kabát, Wolff, Bies: "Stress-induced inactivation of the c-Myb transcription factor through conjugation of SUMO-2/3 proteins." in: The Journal of biological chemistry, Vol. 281, Issue 52, pp. 40065-75, (2006) (PubMed).

Close, Game, Clark, Bergounioux, Gerovassili, Thein: "Genome annotation of a 1.5 Mb region of human chromosome 6q23 encompassing a quantitative trait locus for fetal hemoglobin expression in adults." in: BMC genomics, Vol. 5, Issue 1, pp. 33, (2004) (PubMed).

Synonyms and alternative names related to MYB

MYB proto-oncogene, transcription factor (MYB), myeloblastosis oncogene (Myb), MYB proto-oncogene, transcription factor S homeolog (myb.S), v-myb avian myeloblastosis viral oncogene homolog (myb), MYB proto-oncogene, transcription factor (Myb), AI550390, c-myb, c-myb_CDS, Cmyb, cmyb, efg, M16449, xmyb

Protein level used designations for MYB

  • c-myb protein (140 AA)
  • c-myb10A_CDS
  • c-myb13A_CDS
  • c-myb14A_CDS
  • c-myb8B_CDS
  • proto-oncogene c-Myb
  • transcriptional activator Myb
  • gag-myb protein
  • myb proto-oncogene protein
  • myeloblastosis proto-oncogene product
  • tumor-specific myb protein
  • C-myb
  • myeloblastosis oncogene
  • Avian myeloblastosis viral (v-myb) oncogene homolog
  • v-myb myeloblastosis viral oncogene homolog (avian)
  • transcriptional activator Myb-like
  • DNA-binding transcriptional regulator
  • c-myb proto-oncogene
  • transcription factor cmyb
  • v-myb myeloblastosis viral oncogene homolog
  • v-myb avian myeloblastosis viral oncogene homolog
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