Browse our SF3B1 Proteins (SF3B1)

This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms.

• splicing factor 3b subunit 1 (SF3B1)
• splicing factor 3b, subunit 1 (Sf3b1)
• splicing factor 3b subunit 1 S homeolog (sf3b1.S)
• splicing factor 3b subunit 1 (sf3b1)
• splicing factor 3b, subunit 1 (sf3b1)
• Show all gene names
• splicing factor 3b subunit 1 (Sf3b1)

• 155kDa protein
• 2810001M05Rik protein
• AA409119 protein
• hsh155 protein
• MDS protein
• Show all synonym aliases
• prp10 protein
• prpf10 protein
• Sap155 protein
• SF3B1 protein
• SF3b155 protein
• TA-8 protein
• Targ4 protein
• wu:fb99f09 protein

SAP 155 , pre-mRNA processing 10 , pre-mRNA splicing factor SF3b, 155 kDa subunit , spliceosome-associated protein 155 , splicing factor 3B subunit 1 , pre-mRNA-splicing factor SF3b 155 kDa subunit , splicing factor 3b, subunit 1, 155 kDa , transforming growth factor alpha regulated gene 4 , 146 kDa nuclear protein , SF3b155 , splicing factor 3b, subunit 1, 155kDa , splicing factor 3B subunit 1-like , splicing factor 3b, subunit 1, 155kD , tst