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The findings invoke a model wherein incomplete DNA synthesis during S phase leads to a DNA damage response and formation of 53BP1-OPT domains in the subsequent G1.
SNAP45 plays two roles in the cell, one as a subunit of the transcription factor SNAP(c) and another as a factor required for proper mitotic progression
This gene encodes a subunit of the snRNA-activating protein complex which is associated with the TATA box-binding protein. The encoded protein is necessary for RNA polymerase II and III dependent small-nuclear RNA gene transcription. Alternative splicing results in multiple transcript variants.
small nuclear RNA activating complex, polypeptide 2, 45kDa
, SNAPc 45 kDa subunit
, SNAPc subunit 2
, small nuclear RNA-activating complex polypeptide 2
, snRNA-activating protein complex 45 kDa subunit
, snRNA-activating protein complex subunit 2
, PSE-binding factor subunit delta
, PTF subunit delta
, SNAPC 45 kDa subunit
, proximal sequence element-binding transcription factor subunit delta