Protein Summary

This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. Along with a single, unique beta-chain, seven identical alpha-chains encoded by this gene assemble into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Two pseudogenes of this gene are also found in the cluster.

Alternative names and synonyms associated with C4BPA

• complement component 4 binding protein, alpha chain (LOC419851) antibody
• C4b-binding protein alpha chain (c4bp) antibody
• complement component 4 binding protein alpha (C4BPA) antibody
• complement component 4 binding protein, alpha (C4bpa) antibody

• C4BP antibody
• CRES antibody
• PRP antibody

Protein level used designations for C4BPA

C4b-binding protein alpha chain , complement regulatory soluble protein , proline-rich protein , C4bp , complement component 4 binding protein, alpha chain