C4BPA antibody (AA 49-597)

Catalog No. ABIN7146164

Product Details anti-C4BPA Antibody

Target: C4BPA (Complement Component 4 Binding Protein, alpha (C4BPA))

Binding Specificity: AA 49-597

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C4BPA antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human C4b-binding protein alpha chain protein (49-597AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for C4BPA

Target: C4BPA (Complement Component 4 Binding Protein, alpha (C4BPA))

Alternative Name: C4BPA (C4BPA Products)

Synonyms: CRES antibody, c4bp antibody, C4BP antibody, PRP antibody, complement component 4 binding protein, alpha chain antibody, C4b-binding protein alpha chain antibody, complement component 4 binding protein alpha antibody, complement component 4 binding protein, alpha antibody, LOC419851 antibody, c4bp antibody, C4BPA antibody, C4bpa antibody

Background:

Background: Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component.

Aliases: C4b-binding protein alpha chain antibody, C4bp antibody, C4bpa antibody, C4BPA_HUMAN antibody, Complement component 4 binding protein alpha antibody, Complement component 4 binding protein antibody, Proline-rich protein antibody, PrP antibody, RP11-164O23.4 antibody

UniProt: P04003

Pathways: Complement System